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Catalog Number Size Price
LS-A10808-50 50 µg (1 mg/ml) $460 
EPCAM Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
EPCAM Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
EPCAM Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
EPCAM Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
EPCAM Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
EPCAM Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PathPlus™ Polyclonal Rabbit anti‑Human EPCAM Antibody (IHC) LS‑A10808

PathPlus™ Polyclonal Rabbit anti‑Human EPCAM Antibody (IHC) LS‑A10808

Antibody:
EPCAM Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-A10808-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
EPCAM Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P
Format:
Unconjugated, Unmodified

Specifications

Description
EPCAM (TACSTD1) is an epithelial membrane glycoprotein involved in cell adhesion that is present on the surface of a variety of epithelial cells. It is expressed in a wide variety of cancers, including: basal cell carcinomas, mammary Paget disease, lung adenocarcinomas, trichoepitheliomas, dermatofibromas, basal-cell carcinomas, cholangiocarcinomas, colorectal carcinomas, and carcinomas of prostate, ovary, endometrium, head and neck, and thyroid. EPCAM is useful for distinguishing epithelial cells (positive) from mesothelial cells (negative). It has also been implicated in the progression of individuals with Lynch Syndrome who hold inherited deletions in the gene. These deletions lead to silencing of the adjacent repair gene MSH2 via transcriptional read-through, which then causes microsatellite instability and colorectal cancer (as well as other malignancies that also frequently arise from Lynch Syndrome). MOC31 and BerEP4 are common monoclonal antibodies to this target. References: JClinPathol 1990,43:213; Acta Neuropathol 1991, 83:46; Dai, 2017; Baeuerle, 2007; Kempers 2010; ModPath 2002, 15:1279
Target
Human EPCAM
Synonyms
EPCAM | 323/A3 | ACSTD1 | 17-1A | CD326 | EGP | EGP34 | Epithelial glycoprotein | GA733-2 | HNPCC8 | Ep-CAM | ESA | HEGP314 | KS 1/4 antigen | KS1/4 | KSA | M1S2 | MIC18 | MK-1 | MH99 | TROP1 | TACST-1 | TACSTD1 | CD326 antigen | CO-17A | DIAR5 | EGP-2 | EGP314 | EGP40 | Epithelial glycoprotein 314 | HEA125 | Ly74 | M4S1
Host
Rabbit
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
LP-10808, synthetic peptide
Applications
  • IHC - Paraffin (2.5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About EPCAM
P16422 NM_002354 NP_002345.2

Validation

EPCAM Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

EPCAM Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

EPCAM Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ EPCAM Antibody for IHC LS-A10808 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 7/21/2024