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Catalog Number Size Price
LS-B3189-0.05 0.05 mg (1 mg/ml) $440 
ACIN1 / Acinus Antibody - Anti-ACIN1 / Acinus antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
ACIN1 / Acinus Antibody - Anti-ACIN1 / Acinus antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
ACIN1 / Acinus Antibody - Anti-ACIN1 / Acinus antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
ACIN1 / Acinus Antibody - Immunocytochemistry of Acinus in K562 cells with Acinus antibody at 0.5 µg/ml.
ACIN1 / Acinus Antibody - Immunofluorescence of Acinus in K562 cells with Acinus antibody at 20 ug/ml.
ACIN1 / Acinus Antibody - Western blot of Acinus in K562 whole cell lysate with Acinus antibody at 0.5 ug/ml.
ACIN1 / Acinus Antibody - Anti-ACIN1 / Acinus antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
ACIN1 / Acinus Antibody - Anti-ACIN1 / Acinus antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
ACIN1 / Acinus Antibody - Anti-ACIN1 / Acinus antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
ACIN1 / Acinus Antibody - Immunocytochemistry of Acinus in K562 cells with Acinus antibody at 0.5 µg/ml.
ACIN1 / Acinus Antibody - Immunofluorescence of Acinus in K562 cells with Acinus antibody at 20 ug/ml.
ACIN1 / Acinus Antibody - Western blot of Acinus in K562 whole cell lysate with Acinus antibody at 0.5 ug/ml.
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PathPlus™ Polyclonal Rabbit anti‑Human ACIN1 / Acinus Antibody (IHC, IF, WB) LS‑B3189

PathPlus™ Polyclonal Rabbit anti‑Human ACIN1 / Acinus Antibody (IHC, IF, WB) LS‑B3189

Note: This antibody replaces LS-C329, LS-C57045, LS-C57046, LS-C42849, LS-C11732, LS-C42848
Antibody:
ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, ICC, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B3189-0.05
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, ICC, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
ACIN1 is an auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs, and it is a part of the ASAP complex that is recruited to the EJC during the splicing process. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. ACIN1 is also involved in the splicing modulation of BCL2L1/Bcl-X and probably other apoptotic genes. It specifically inhibits the formation of proapoptotic isoforms such as Bcl-X(S). Furtehrmore, it induces apoptotic chromatin condensation after activation by CASP3. Finally, it regulates cyclin A1, but not cyclin A2, expression in leukemia cells. In immunohistochemistry, ACIN1 as nuclear positivity in all tissues throughout the body. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human ACIN1 / Acinus
Synonyms
ACIN1 | ACINUS | ACN | KIAA0670 | FSAP152
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Peptide Column Affinity Chromatography
Modifications
Unmodified
Immunogen
A peptide corresponding to amino acids near the carbosy terminus of human AcinusL, which are identical to those of mouse Acinus. The immunogen is located within the last 50 amino acids of Acinus.
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • ICC
  • Immunofluorescence
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Acinus antibody antibody can be used for detection of Acinus by Western blot at 0.5 ug/mL. An approximate 220 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 0.5 ug/mL. For immunofluorescence start at 20 ug/mL. Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Western Blot: 220 kDa
Presentation
PBS containing 0.02% Sodium Azide
Storage
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ACIN1 / Acinus
Q9UKV3 NM_014977 NP_055792.1

Validation

ACIN1 / Acinus Antibody - Anti-ACIN1 / Acinus antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACIN1 / Acinus antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACIN1 / Acinus antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

ACIN1 / Acinus Antibody - Anti-ACIN1 / Acinus antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACIN1 / Acinus antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACIN1 / Acinus antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

ACIN1 / Acinus Antibody - Anti-ACIN1 / Acinus antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACIN1 / Acinus antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACIN1 / Acinus antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

LSBio Ratings

PathPlus™ ACIN1 / Acinus Antibody for IHC, ICC, IF/Immunofluorescence, WB/Western, ELISA LS-B3189 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

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Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/23/2024