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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-A1001-50 50 µg (1 mg/ml) $425 
SSTR2 Antibody - Anti-SSTR2 antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PathPlus™ SSTR2 Antibody C‑Terminus Polyclonal IHC LS‑A1001

PathPlus™ SSTR2 Antibody C‑Terminus Polyclonal IHC LS‑A1001

Antibody:
Rabbit Polyclonal to Human SSTR2
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Chicken, Xenopus
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A1001-50
50 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human SSTR2
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Chicken, Xenopus
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
SSTR2A (somatostatin receptor 2A) is one of the two isoforms of the somatostatin receptor 2, a G-protein coupled receptor for somatostatin-14 and somatostatin-28. Binding to the receptor inhibits adenylyl cyclase and calcium channels, resulting in several organ-specific functions, including inhibition of secretion of glucagon and insulin in the pancreas, inhibiting secretion of gastric acid, pepsin, and bile in the GI tract, and inhibiting secretion of neurotransmitters in the brain. The receptor thereby affects the body’s locomotor, sensory, autonomic and cognitive functions. Also, somatostatin can cause cell cycle arrest, as well as induce agonist-dependent endocytosis. The receptor also binds synthetic somatostatin (octreotide), which can be used to image or target somatostatin-secreting neuroendocrine tumors. It is mostly expressed in the cell membrane of pancreatic alpha and beta cells, various regions of the brain, the adrenal medulla and neuroendocrine cells. Oncol Lett 2017 13(3):1165; Cell Phys Biochem 2002 12(1):31; Am J Phys Endoc Metab 2012 303(9):E1107; Bioch Biphys Acta 2001 1616(1):1
Target
Human SSTR2
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Chicken, Xenopus (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (16 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 16 amino acid peptide from C-terminus of human SSTR2. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Bat, Bovine, Dog, Hamster, Elephant, Panda, Horse, Pig, Opossum, Chicken, Platypus, Xenopus (100%); Lizard (94%).
Blocking Peptide
LS-E28091 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A1001. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
Human SSTR2 isoform A per Uniprot P30874. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SSTR2
P30874 NM_001050 NP_001041.1

Validation

SSTR2 Antibody - Anti-SSTR2 antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SSTR2 antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SSTR2 antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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Requested From: United States
Date Requested: 11/19/2019