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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A389-50 50 µg (1 mg/ml) $425 
P2RY1 / P2Y1 Antibody - Brain, Hypothalamus
P2RY1 / P2Y1 Antibody - Anti-P2RY1 / P2Y1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
P2RY1 / P2Y1 Antibody - Brain, cortex, neurons
P2RY1 / P2Y1 Antibody - pancreas, Adenocarcinoma
P2RY1 / P2Y1 Antibody - Brain, Hypothalamus
P2RY1 / P2Y1 Antibody - Anti-P2RY1 / P2Y1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
P2RY1 / P2Y1 Antibody - Brain, cortex, neurons
P2RY1 / P2Y1 Antibody - pancreas, Adenocarcinoma
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PathPlus™ Polyclonal P2RY1 / P2Y1 Antibody (C‑Terminus, IHC) LS‑A389

PathPlus™ Polyclonal P2RY1 / P2Y1 Antibody (C‑Terminus, IHC) LS‑A389

Antibody:
Rabbit Polyclonal to Human P2RY1 / P2Y1
Application:
IHC, IHC-P, ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A389-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human P2RY1 / P2Y1
Application:
IHC, IHC-P, ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Purinergic receptor P2Y, G-protein coupled, 1 (P2RY1) has several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. P2RY1 functions as a receptor for extracellular ATP and ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human P2RY1 / P2Y1
Synonyms
P2RY1 | ATP receptor | p2Y1 | p2y1r | Platelet ADP receptor | Purinoceptor p2y1 | Purinergic receptor | p2 purinoceptor subtype Y1 | p2RY1 | p2Y purinoceptor 1 | p2y-1-r | Purinoceptor p2yr1 | p2y1 receptor
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Chicken, Xenopus (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (6 µg/ml)
  • ELISA
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 19 amino acid peptide from C-Terminus of human P2RY1 / P2Y1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bat, Dog, Bovine, Horse, Rabbit, Opossum, Guinea pig, Lizard (100%); Panda, Turkey, Chicken, Platypus, Xenopus (95%).
Blocking Peptide
LS-E28834 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A389. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
Human P2RY1 / P2Y1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About P2RY1 / P2Y1
P47900 NM_002563 NP_002554.1

Validation

P2RY1 / P2Y1 Antibody - Brain, Hypothalamus
Brain, Hypothalamus
Brain, Hypothalamus

P2RY1 / P2Y1 Antibody - Anti-P2RY1 / P2Y1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY1 / P2Y1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY1 / P2Y1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

P2RY1 / P2Y1 Antibody - Brain, cortex, neurons
Brain, cortex, neurons
Brain, cortex, neurons

P2RY1 / P2Y1 Antibody - pancreas, Adenocarcinoma
pancreas, Adenocarcinoma
pancreas, Adenocarcinoma

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Requested From: United States
Date Requested: 2/18/2020