Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
P2RY1 / P2Y1 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
|Gene Name:||purinergic receptor P2Y, G-protein coupled, 1|
|Family/Subfamily:||GPCR , Purinergic|
|Synonyms:||P2RY1, ATP receptor, p2Y1, p2y1r, Platelet ADP receptor, Purinoceptor p2y1, Purinergic receptor, p2 purinoceptor subtype Y1, p2RY1, p2Y purinoceptor 1, p2y-1-r, Purinoceptor p2yr1, p2y1 receptor|
|Target Sequences:||NM_002563 NP_002554.1 P47900|
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