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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A7186-50 50 µg (1 mg/ml) $425 
MST1R / RON Antibody - Bone marrow, macrophages
MST1R / RON Antibody - Small Intestine, Crohn's Disease
MST1R / RON Antibody - Brain Cortex Neuron
MST1R / RON Antibody - Lung, Bronchitis
MST1R / RON Antibody - Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MST1R / RON Antibody - Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MST1R / RON Antibody - Anti-MST1R / RON antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MST1R / RON Antibody - Bone marrow, macrophages
MST1R / RON Antibody - Small Intestine, Crohn's Disease
MST1R / RON Antibody - Brain Cortex Neuron
MST1R / RON Antibody - Lung, Bronchitis
MST1R / RON Antibody - Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MST1R / RON Antibody - Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MST1R / RON Antibody - Anti-MST1R / RON antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ MST1R / RON Antibody C‑Terminus Polyclonal IHC LS‑A7186

PathPlus™ MST1R / RON Antibody C‑Terminus Polyclonal IHC LS‑A7186

Antibody:
Rabbit Polyclonal to Human MST1R / RON
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A7186-50
50 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human MST1R / RON
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Macrophage stimulating 1 receptor (c-met-related tyrosine kinase, MST1R) regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, it interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. It also plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human MST1R / RON
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (4 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 18 amino acid peptide from C-terminus of human MST1R / RON. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Marmoset (94%); Mouse, Rat, Hamster, Elephant, Panda, Horse (89%); Dog, Bat (83%).
Blocking Peptide
LS-E29237 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A7186. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
Human MST1R / RON. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MST1R / RON
Q04912 NM_002447 NP_002438.2

Validation

MST1R / RON Antibody - Bone marrow, macrophages
Bone marrow, macrophages
Bone marrow, macrophages

MST1R / RON Antibody - Small Intestine, Crohn's Disease
Small Intestine, Crohn's Disease
Small Intestine, Crohn's Disease

MST1R / RON Antibody - Brain Cortex Neuron
Brain Cortex Neuron
Brain Cortex Neuron

MST1R / RON Antibody - Lung, Bronchitis
Lung, Bronchitis
Lung, Bronchitis

MST1R / RON Antibody - Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MST1R / RON Antibody - Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MST1R / RON Antibody - Anti-MST1R / RON antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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Requested From: United States
Date Requested: 11/21/2019