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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MST1R / RON

macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.

Gene Name: macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
Family/Subfamily: Protein Kinase , HGF Receptor/MET
Synonyms: MST1R, C-met-related tyrosine kinase, CD136, CDw136, CD136 antigen, Friend virus susceptibility 2, Fv2, MSP receptor, p185-Ron, PTK8 protein tyrosine kinase 8, RON, Soluble RON variant 3, Soluble RON variant 1, MST1R variant RON30, Oncogene RON, PTK8, MST1R variant RON62, Protein-tyrosine kinase 8, RON variant E2E3, Soluble RON variant 2, Soluble RON variant 4
Target Sequences: NM_002447 NP_002438.2 Q04912

Filtered by: None
Target
MST1R / RON (114)
Reactivity
Human (98)
Mouse (23)
Rat (1)
Bat (7)
Monkey (14)
Application
IHC (44)
IHC-P (37)
WB (66)
Flo (2)
ELISA (58)
IF (1)
IP (1)
Peptide-ELISA (1)
Host
rabbit (105)
mouse (7)
goat (2)
Isotype
Ig (1)
IgG (50)
IgG1 (2)
IgG2a (2)
IgG2a,k (1)
Clonality
monoclonal mc (7)
polyclonal pc (107)
Clone
1B5A9 (2)
4E2 (1)
OTI1D12 (2)
Format
AP Conjugated (9)
APC (2)
APC Conjugated (11)
Azide-free (9)
Biotin Conjugated (11)
Carrier-free (1)
CF Conjugated (1)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (11)
HRP Conjugated (11)
PE Conjugated (12)
Unconjugated (44)
Epitope
C-Terminus (15)
Internal (15)
N-Terminus (14)
aa1013-1041 (8)
aa1092-1316 (8)
aa89-275 (8)
aa25-304 (2)
1330-1410 aa (1)
31-80 aa, N-terminal (1)
Amino Acid: 210-320 (1)
pSer1394 (1)
pTyr1353 (1)
pTyr1360 (1)
Publications
No (114)
Showing 1-25 of 114 results

IHC-plus™ MST1R / RON Antibody (Internal) LS-A7185
Rabbit Polyclonal to Human MST1R / RON
Human
ELISA, IHC, IHC-P
Unconjugated
50µg 1mg/ml  $425.00
Anti-MST1R / RON antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (Internal, Biotin) LS-A106867
Rabbit Polyclonal to Human MST1R / RON
Human
ELISA, IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-MST1R / RON antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (Internal, FITC) LS-A106868
Rabbit Polyclonal to Human MST1R / RON
Human
ELISA, IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-MST1R / RON antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (Internal, APC) LS-A106866
Rabbit Polyclonal to Human MST1R / RON
Human
ELISA, IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-MST1R / RON antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (Internal, Azide-free, HRP) LS-A106869
Rabbit Polyclonal to Human MST1R / RON
Human
ELISA, IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-MST1R / RON antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (Internal, AP) LS-A106865
Rabbit Polyclonal to Human MST1R / RON
Human
ELISA, IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-MST1R / RON antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (Internal, PE) LS-A106870
Rabbit Polyclonal to Human MST1R / RON
Human
ELISA, IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-MST1R / RON antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MST1R / RON Antibody (aa1013-1041) LS-C164490
Rabbit Polyclonal to Mouse MST1R / RON
Mouse
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Mouse Mst1r Antibody immunohistochemistry of formalin-fixed and paraffin-embedded mouse live tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Mouse Mst1r Antibody western blot of mouse liver tissue lysates (35 ug/lane). The Mst1r antibody detected the Mst1r protein (arrow).

IHC-plus™ MST1R / RON Antibody (C-Terminus) LS-A7186
Rabbit Polyclonal to Human MST1R / RON
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (C-Terminus, Biotin) LS-A106873
Rabbit Polyclonal to Human MST1R / RON
Human
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (C-Terminus, FITC) LS-A106874
Rabbit Polyclonal to Human MST1R / RON
Human
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (C-Terminus, AP) LS-A106871
Rabbit Polyclonal to Human MST1R / RON
Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (C-Terminus, Azide-free, HRP) LS-A106875
Rabbit Polyclonal to Human MST1R / RON
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (C-Terminus, APC) LS-A106872
Rabbit Polyclonal to Human MST1R / RON
Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (C-Terminus, PE) LS-A106876
Rabbit Polyclonal to Human MST1R / RON
Human
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-MST1R / RON antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MST1R / RON antibody IHC of human colon carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MST1R / RON Antibody LS-C194040
Rabbit Polyclonal (IgG) to Human MST1R / RON
Human
IP, WB
Unconjugated
100µg 1ml  $860.00

IHC-plus™ MST1R / RON Antibody (Internal) LS-A7187
Rabbit Polyclonal to Human MST1R / RON
Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-MST1R / RON antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MST1R / RON Antibody (N-Terminus) LS-A7191
Rabbit Polyclonal to Human MST1R / RON
Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-MST1R / RON antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MST1R / RON Antibody (C-Terminus) LS-C137088
Rabbit Polyclonal (IgG) to Human MST1R / RON
Human
ELISA, IHC
Unconjugated
100µl  $275.00
Immunohistochemistry Image

MST1R / RON Antibody (clone 1B5A9) LS-C108881
Mouse Monoclonal [clone 1B5A9] (IgG1) to Human MST1R / RON
Human
ELISA, WB
Unconjugated
100µl  $345.00
Western blot using RON mouse monoclonal antibody against HCC827 (1), HT-29 (2), HCT-116 (3) and BxPC-3 (4) cell lysate.

MST1R / RON Antibody LS-C415764
Rabbit Polyclonal to Human MST1R / RON
Mouse, Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $305.00
Western blot of extracts from HepG2 cells, using RON (Ab-1353) antibody.

MST1R / RON Antibody (aa89-275) LS-C295273
Rabbit Polyclonal to Mouse MST1R / RON
Mouse
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $515.00
Western blot of recombinant MST1R / RON.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MST1R / RON Antibody LS-C800238
Rabbit Polyclonal (IgG) to Human MST1R / RON
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image

MST1R / RON Antibody (aa1013-1041) LS-C329855
Rabbit Polyclonal (IgG) to Mouse MST1R / RON
Mouse
IHC, IHC-P, WB
Unconjugated
200µl  $590.00

MST1R / RON Antibody LS-C484159
Rabbit Polyclonal to Human MST1R / RON
Human
ELISA, IHC, IHC-P
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00
Showing 1-25 of 114 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).