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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A882-50 50 µg (1 mg/ml) $425 
GRM1 / MGLUR1 Antibody - Brain, Thalamus, neurons
GRM1 / MGLUR1 Antibody - Spinal Cord neurons
GRM1 / MGLUR1 Antibody - Anti-GRM1 / MGLUR1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM1 / MGLUR1 Antibody - Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM1 / MGLUR1 Antibody - Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM1 / MGLUR1 Antibody - Brain, Thalamus, neurons
GRM1 / MGLUR1 Antibody - Spinal Cord neurons
GRM1 / MGLUR1 Antibody - Anti-GRM1 / MGLUR1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM1 / MGLUR1 Antibody - Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM1 / MGLUR1 Antibody - Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal GRM1 / MGLUR1 Antibody (C‑Terminus, IHC) LS‑A882

PathPlus™ Polyclonal GRM1 / MGLUR1 Antibody (C‑Terminus, IHC) LS‑A882

Antibody:
Rabbit Polyclonal to Human GRM1 / MGLUR1
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A882-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human GRM1 / MGLUR1
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Glutamate receptor, metabotropic 1 (GRM1) is a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GRM1 / MGLUR1
Synonyms
GRM1 | GRM1A | GPRC1A | MGlu1 | MGLUR1 | SCAR13 | MGLUR1A
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 16 amino acid peptide from C-Terminus of human GRM1 / MGLUR1. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%); Rabbit (81%).
Blocking Peptide
LS-E29490 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A882. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
Human GRM1 / MGLUR1, isoform alpha. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GRM1 / MGLUR1
Q13255 NM_000838 NP_000829.2

Validation

GRM1 / MGLUR1 Antibody - Brain, Thalamus, neurons
Brain, Thalamus, neurons
Brain, Thalamus, neurons

GRM1 / MGLUR1 Antibody - Spinal Cord neurons
Spinal Cord neurons
Spinal Cord neurons

GRM1 / MGLUR1 Antibody - Anti-GRM1 / MGLUR1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM1 / MGLUR1 Antibody - Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM1 / MGLUR1 Antibody - Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ GRM1 / MGLUR1 Antibody (C-Terminus) for IHC LS-A882 has an LSBio Rating of
Laboratory Validation Score (5)

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Requested From: United States
Date Requested: 3/28/2020