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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GRM1 / MGLUR1

glutamate receptor, metabotropic 1

GRM1 / MGLUR1 is a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: glutamate receptor, metabotropic 1
Family/Subfamily: GPCR , Metabotropic glutamate
Synonyms: GRM1, GRM1A, GPRC1A, MGlu1, MGLUR1, SCAR13, MGLUR1A
Target Sequences: NM_000838 NP_000829.2 Q13255

Filtered by: None
Target
GRM1 / MGLUR1 (74)
Reactivity
Human (68)
Mouse (16)
Rat (20)
Bat (1)
Bovine (8)
Chicken (1)
Dog (1)
Hamster (1)
Horse (1)
Monkey (14)
Rabbit (7)
Application
IHC (47)
IHC-Fr (2)
IHC-P (25)
WB (45)
ELISA (28)
ICC (1)
IF (3)
Peptide-ELISA (1)
Host
rabbit (71)
mouse (3)
Isotype
IgG (33)
IgG1 (1)
IgG2a (1)
IgG2b,k (1)
Clonality
monoclonal mc (3)
polyclonal pc (71)
Clone
1F7 (1)
5E12D8 (1)
Format
AP Conjugated (5)
APC (1)
APC Conjugated (6)
Azide-free (5)
Biotin Conjugated (7)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (6)
Unconjugated (34)
Epitope
C-Terminus (26)
aa1095-1123 (8)
aa165-592 (8)
N-Terminus (7)
220-300 aa, Internal (1)
Internal (1)
aa1115-1130 (1)
aa1159-1171 (1)
aa1180-1199 (1)
aa251-300 (1)
aa33-522 (1)
Publications
No (74)
Showing 1-25 of 74 results

IHC-plus™ GRM1 / MGLUR1 Antibody (C-Terminus) LS-A882
Rabbit Polyclonal to Human GRM1 / MGLUR1
Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM1 / MGLUR1 Antibody (C-Terminus, Biotin) LS-A108373
Rabbit Polyclonal to Human GRM1 / MGLUR1
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM1 / MGLUR1 Antibody (C-Terminus, FITC) LS-A108374
Rabbit Polyclonal to Human GRM1 / MGLUR1
Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM1 / MGLUR1 Antibody (C-Terminus, AP) LS-A108371
Rabbit Polyclonal to Human GRM1 / MGLUR1
Human, Monkey
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM1 / MGLUR1 Antibody (C-Terminus, APC) LS-A108372
Rabbit Polyclonal to Human GRM1 / MGLUR1
Human, Monkey
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM1 / MGLUR1 Antibody (C-Terminus, Azide-free, HRP) LS-A108375
Rabbit Polyclonal to Human GRM1 / MGLUR1
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM1 / MGLUR1 Antibody (C-Terminus, PE) LS-A108376
Rabbit Polyclonal to Human GRM1 / MGLUR1
Human, Monkey
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM1 / MGLUR1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM1 / MGLUR1 Antibody (C-Terminus) LS-B1921
Rabbit Polyclonal to Human GRM1 / MGLUR1
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µg 0.2mg/ml  $425.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.

IHC-plus™ GRM1 / MGLUR1 Antibody (N-Terminus) LS-A879
Rabbit Polyclonal to Human GRM1 / MGLUR1
Rabbit, Bovine, Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM1 / MGLUR1 Antibody (N-Terminus, APC) LS-A108324
Rabbit Polyclonal to Human GRM1 / MGLUR1
Rabbit, Bovine, Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM1 / MGLUR1 Antibody (N-Terminus, AP) LS-A108323
Rabbit Polyclonal to Human GRM1 / MGLUR1
Rabbit, Bovine, Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM1 / MGLUR1 Antibody (Internal) LS-C354444
Rabbit Polyclonal to Human GRM1 / MGLUR1
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of mGLUR1 expression in A549 (A) whole cell lysates.

GRM1 / MGLUR1 Antibody (aa1159-1171) LS-C49120
Rabbit Polyclonal to Human GRM1 / MGLUR1
Chicken, Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µg 1mg/ml  $335.00
GluR1: Immunofluorescence labeling for GluR1 in rat brain (cingulate cortex). GluR1 detection was done using anti-rabbit Cy3 conjugated antibodies (red color). DAPI was used to counterstain cell nuclei (blue color). Working dilution is 1:100-1:500.
P2Y2 staining (red color) in rat dorsal root ganglion. Tissue was fixed in 4% paraformaldehyde and cut into 10 micron sections. P2Y2 antibody was used at a dilution of 1:200 and secondary antibody at a dilution of 1:5000.

GRM1 / MGLUR1 Antibody (aa33-522) LS-C124100
Mouse Monoclonal (IgG2a) to Human GRM1 / MGLUR1
Human
ELISA, IHC
Unconjugated
100µg  $650.00

IHC-plus™ GRM1 / MGLUR1 Antibody (clone 1F7) LS-B9907
Mouse Monoclonal [clone 1F7] (IgG2b,k) to Human GRM1 / MGLUR1
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg  $495.00
Anti-GRM1 / MGLUR1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Detection limit for recombinant GST tagged GRM1 is 0.1 ng/ml as a capture antibody.

GRM1 / MGLUR1 Antibody (aa1180-1199) LS-C25607
Rabbit Polyclonal (IgG) to Rat GRM1 / MGLUR1
Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat
ICC, IHC, IHC-Fr, WB
Unconjugated
50µg  $680.00

GRM1 / MGLUR1 Antibody LS-C40779
Rabbit Polyclonal (IgG) to Human GRM1 / MGLUR1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg 100µl 1mg/ml  $275.00

GRM1 / MGLUR1 Antibody (C-Terminus) LS-C209
Rabbit Polyclonal to Rat GRM1 / MGLUR1
Rat
IHC, WB
Unconjugated
100µl  $375.00
Western blot of 10 ug of HEK 293 cells expressing mGluR1a and mGluR5 showing the specific immunolabeling of the -125k monomer and the -250k dimer of mGluR1a. The mGluR1a antibody shows no reactivity toward mGluR5.

GRM1 / MGLUR1 Antibody (aa1095-1123) LS-C166684
Rabbit Polyclonal to Human GRM1 / MGLUR1
Human
WB
Unconjugated
400µl  $325.00
GRM1 Antibody western blot of CEM cell line lysates (35 ug/lane). The GRM1 antibody detected the GRM1 protein (arrow).

GRM1 / MGLUR1 Antibody LS-C806502
Rabbit Polyclonal (IgG) to Human GRM1 / MGLUR1
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

GRM1 / MGLUR1 Antibody LS-C498992
Rabbit Polyclonal (IgG) to Human GRM1 / MGLUR1
Human
ELISA, IF, IHC
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human brain tissue using GRM1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using GRM1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

GRM1 / MGLUR1 Antibody LS-C402364
Rabbit Polyclonal (IgG) to Human GRM1 / MGLUR1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl 0.3mg/ml  $205.00; 60µl 0.3mg/ml  $235.00; 120µl 0.3mg/ml  $295.00; 200µl 0.3mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human breast cancer using GRM1 Polyclonal Antibody at dilution of 1:15.
Immunohistochemistry of paraffin-embedded Human brain using GRM1 Polyclonal Antibody at dilution of 1:15.

IHC-plus™ GRM1 / MGLUR1 Antibody (C-Terminus) LS-A880
Rabbit Polyclonal to Human GRM1 / MGLUR1
Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM1 / MGLUR1 Antibody (C-Terminus) LS-C322969
Rabbit Polyclonal (IgG) to Human GRM1 / MGLUR1
Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

GRM1 / MGLUR1 Antibody (C-Terminus) LS-C153486
Rabbit Polyclonal to Human GRM1 / MGLUR1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
200µl  $305.00
Showing 1-25 of 74 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).