Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Features: - Inhibits endogenous peroxidase, pseudoperoxidase, and alkaline phosphatase activities - Provided in a convenient dropper bottle - Ready-to-use in convenient dropper bottle - Simple one-step protocol - Compatible with formalin-fixed, paraffin-embedded tissue sections, frozen tissue sections, and cell preparations - More effective than conventional blocking methods Components: - 100 ml of Ready-to-Use BLOXALL™ Endogenous Peroxidase and Alkaline Phosphatase Blocking Solution Applications: - Immunohistochemistry - Immunocytochemistry - Immunofluorescence - In situ hybridization - Neurobiology - Blocking Action Autofluorescence Details: Tissues can contain endogenous peroxidase, pseudoperoxidase, and/or alkaline phosphatase activity that will produce background staining if an alkaline phosphatase and/or peroxidase detection system and corresponding substrates are used. BLOXALL™ Endogenous Peroxidase and Alkaline Phosphatase Blocking Solution is a dual enzyme blocking reagent that inactivates endogenous peroxidase, pseudoperoxidase, and alkaline phosphatase in formalin-fixed, paraffin-embedded tissue sections, frozen tissue sections, and cell preparations in a single 10 minute incubation step. This reagent is provided as a ready-to-use reagent in a convenient dropper bottle.