Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Iron Responsive Element Binding Protein 2 (IREB2)
No significant cross-reactivity or interference between Iron Responsive Element Binding Protein 2 (IREB2) and analogs was observed.
LS-F8596 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Rat IREB2 / IRP2 in samples of Tissue Homogenates. It is based upon a Sandwich assay principle and can be used to detect levels of IREB2 / IRP2 as low as 0.108 nanograms per millilter.
96-Well Strip Plate
Colorimetric - 450nm (TMB)
0.313 - 20 ng/ml
Intra-Assay: CV<10% Inter-Assay: CV<12%
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
IREB2 ElisaKit, ACO3 ElisaKit, Iron regulatory protein 2 ElisaKit, IRP2AD ElisaKit, IRE-BP 2 ElisaKit, IRP2 ElisaKit
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.