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| Catalog Number | Size | Price |
|---|---|---|
| LS-B1572-50 | 50 µl (0.5 mg/ml) | $460 |
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Polyclonal Rabbit anti‑Human ZFP36 / Tristetraprolin Antibody (aa84‑133, IHC, WB) LS‑B1572
Polyclonal Rabbit anti‑Human ZFP36 / Tristetraprolin Antibody (aa84‑133, IHC, WB) LS‑B1572
Note: This antibody replaces LS-C29984
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
Tristetraprolin antibody LS-B1572 is an unconjugated rabbit polyclonal antibody to human Tristetraprolin (ZFP36) (aa84-133). Validated for IHC and WB. Cited in 3 publications.
Target
Human ZFP36 / Tristetraprolin
Synonyms
ZFP36 | Protein TIS11A | Tristetraprolin | ZFP36 ring finger protein | TIS11 | Zinc finger protein 36 homolog | TTP | NUP475 | TIS11A | Tristetraproline | Zfp-36 | G0S24 | GOS24 | RNF162A
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide located between aa84-133 of human ZFP36 (P26651, NP_003398). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon (100%); Marmoset, Mouse, Rat, Sheep, Panda, Dog, Bovine, Rabbit, Guinea pig (85%); Elephant (83%).
Epitope
aa84-133
Specificity
Human ZFP36
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot (0.2 - 1 µg/ml)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B1572 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1572 was determined to be 5 ug/ml.
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ZFP36 / Tristetraprolin
LSBio Ratings
ZFP36 / Tristetraprolin Antibody (aa84-133) for IHC, WB/Western LS-B1572 has an LSBio Rating of
Publications (4.2)
Learn more about The LSBio Ratings Algorithm
Publications (3)
RNA binding protein, tristetraprolin in a murine model of recurrent pregnancy loss. Khalaj K, Luna RL, de França ME, de Oliveira WH, Peixoto CA, Tayade C. Oncotarget. 2016 7:72486-72502. (Mouse)
Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients. Ricciardi L, Col JD, Casolari P, Memoli D, Conti V, Vatrella A, Vonakis BM, Papi A, Caramori G, Stellato C. International journal of chronic obstructive pulmonary disease. 2018 October;13:3173-3190.
Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization. William J Sullivan, Peter J Mullen, Ernst W Schmid, Aimee Flores, Milica Momcilovic, Mark S Sharpley, David Jelinek, Andrew E Whiteley, Matthew B Maxwell, Blake R Wilde, Utpal Banerjee, Hilary A Coller, David B Shackelford, Daniel Braas, Donald E Ayer, Thomas Q de Aguiar Vallim, William E Lowry, Heather R Christofk. Cell. 2018 September;175:117-132.e21.
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
Immunofluorescence, Western blot, Flow Cytometry
Species:
Human
Applications:
Western blot
Reactivity:
Human
Range:
31.2-2000 pg/ml
Source:
Human
Tag:
Myc-DDK (Flag)
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/26/2024
Date Requested: 4/26/2024
