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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
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Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
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ZFP36 / Tristetraprolin

ZFP36 ring finger protein

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).

Gene Name: ZFP36 ring finger protein
Synonyms: ZFP36, Protein TIS11A, Tristetraprolin, ZFP36 ring finger protein, TIS11, Zinc finger protein 36 homolog, TTP, NUP475, TIS11A, Tristetraproline, Zfp-36, G0S24, GOS24, RNF162A
Target Sequences: NM_003407 NP_003398.2 P26651

Publications (3)

1
RNA binding protein, tristetraprolin in a murine model of recurrent pregnancy loss. Khalaj K, Luna RL, de França ME, de Oliveira WH, Peixoto CA, Tayade C. Oncotarget. 2016 7:72486-72502. (Mouse) [Full Text Article] [PubMed:27732963] [PMC:PMC5341924] Related Antibodies: LS-B1572.
2
Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients. Ricciardi L, Col JD, Casolari P, Memoli D, Conti V, Vatrella A, Vonakis BM, Papi A, Caramori G, Stellato C. International journal of chronic obstructive pulmonary disease. 2018 October;13:3173-3190. [Full Text Article] [PubMed:30349226] [PMC:PMC6190813] Related Antibodies: LS-B1572.
3
Tristetraprolin Is a Prognostic Biomarker for Poor Outcomes among Patients with Low-Grade Prostate Cancer. Rounbehler RJ, Berglund AE, Gerke T, Takhar MM, Awasthi S, Li W, Davicioni E, Erho NG, Ross AE, Schaeffer EM, Klein EA, Karnes RJ, Jenkins RB, Cleveland JL, Park JY, Yamoah K. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2018 November;27:1376-1383. [Full Text Article] [PubMed:30108099] [PMC:PMC6214732] Related Antibodies: LS-B5606.


ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human ZFP36 / Tristetraprolin
Human
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $485.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human ZFP36 / Tristetraprolin
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $485.00
ZFP36 / Tristetraprolin Antibody - Heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human ZFP36 / Tristetraprolin
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human
IHC, IHC-P, WB
Biotin Conjugated
100µl   1mg/ml   $405.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 antibody IHC of human small intestine, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human ZFP36 / Tristetraprolin
Rabbit, Dog, Guinea pig, Sheep, Bovine, Pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI1H6] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated
100µl   $345.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI1H6] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
ZFP36 / Tristetraprolin Antibody - Immunohistochemical staining of paraffin-embedded colon tissue using anti-ZFP36 mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI8B5] (IgG1) to Human ZFP36 / Tristetraprolin
Flo, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
ZFP36 / Tristetraprolin Antibody - Immunohistochemical staining of paraffin-embedded colon tissue using anti-ZFP36 mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI8B5] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
ZFP36 / Tristetraprolin Antibody - IHC of paraffin-embedded Human breast tissue using anti-ZFP36 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
Mouse Monoclonal [clone OTI1A2] (IgG2a) to Human ZFP36 / Tristetraprolin
Human
Flo, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
ZFP36 / Tristetraprolin Antibody - IHC of paraffin-embedded Human breast tissue using anti-ZFP36 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
Mouse Monoclonal [clone OTI1A2] (IgG2a) to Human ZFP36 / Tristetraprolin
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
ZFP36 / Tristetraprolin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFP36 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFP36.
Select
Mouse Monoclonal [clone OTI5E3] (IgG1) to Human ZFP36 / Tristetraprolin
Human
WB
Unconjugated
100µl   0.47mg/ml   $345.00
Select
Rabbit Polyclonal (IgG) to Human ZFP36 / Tristetraprolin
Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $435.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI1C8] (IgG2a) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated
100µl   0.95mg/ml   $345.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI1C8] (IgG2a) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI4E1] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated
100µl   0.55mg/ml   $345.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI4E1] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI3C3] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated
100µl   0.36mg/ml   $345.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI3C3] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI1F2] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated
100µl   0.51mg/ml   $345.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI1F2] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
ZFP36 / Tristetraprolin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFP36 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFP36.
Select
Mouse Monoclonal [clone OTI4B10] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, WB
Unconjugated
100µl   0.68mg/ml   $345.00
ZFP36 / Tristetraprolin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFP36 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFP36.
Select
Mouse Monoclonal [clone OTI4B10] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, WB
Unconjugated, Carrier-free
100µg   $395.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI3D10] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF
Unconjugated
100µl   0.69mg/ml   $345.00
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
Mouse Monoclonal [clone OTI3D10] (IgG1) to Human ZFP36 / Tristetraprolin
Human
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Rabbit Polyclonal to Human ZFP36 / Tristetraprolin
Human
ELISA, IHC, WB
Unconjugated
50µg   $285.00; 100µg   1mg/ml   $355.00
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).