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ZFP36 / Tristetraprolin

ZFP36 ring finger protein

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).

Gene Name: ZFP36 ring finger protein
Synonyms: ZFP36, Protein TIS11A, Tristetraprolin, ZFP36 ring finger protein, TIS11, Zinc finger protein 36 homolog, TTP, NUP475, TIS11A, Tristetraproline, Zfp-36, G0S24, GOS24, RNF162A
Target Sequences: NM_003407 NP_003398.2 P26651

Publications (4)

1
RNA binding protein, tristetraprolin in a murine model of recurrent pregnancy loss. Khalaj K, Luna RL, de França ME, de Oliveira WH, Peixoto CA, Tayade C. Oncotarget. 2016 7:72486-72502. (Mouse) [Full Text Article] [PubMed:27732963] [PMC:PMC5341924] Related Antibodies: LS-B1572.
2
Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients. Ricciardi L, Col JD, Casolari P, Memoli D, Conti V, Vatrella A, Vonakis BM, Papi A, Caramori G, Stellato C. International journal of chronic obstructive pulmonary disease. 2018 October;13:3173-3190. [Full Text Article] [PubMed:30349226] [PMC:PMC6190813] Related Antibodies: LS-B1572.
3
Tristetraprolin Is a Prognostic Biomarker for Poor Outcomes among Patients with Low-Grade Prostate Cancer. Rounbehler RJ, Berglund AE, Gerke T, Takhar MM, Awasthi S, Li W, Davicioni E, Erho NG, Ross AE, Schaeffer EM, Klein EA, Karnes RJ, Jenkins RB, Cleveland JL, Park JY, Yamoah K. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2018 November;27:1376-1383. [Full Text Article] [PubMed:30108099] [PMC:PMC6214732] Related Antibodies: LS-B5606.
4
Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization. William J Sullivan, Peter J Mullen, Ernst W Schmid, Aimee Flores, Milica Momcilovic, Mark S Sharpley, David Jelinek, Andrew E Whiteley, Matthew B Maxwell, Blake R Wilde, Utpal Banerjee, Hilary A Coller, David B Shackelford, Daniel Braas, Donald E Ayer, Thomas Q de Aguiar Vallim, William E Lowry, Heather R Christofk. Cell. 2018 September;175:117-132.e21. [Full Text Article] [PubMed:30197082] [PMC:PMC6151140] Related Antibodies: LS-B1572.
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Antibodies (53)
Primary (53)
ZFP36 / Tristetraprolin (53)
Human (52)
Mouse (6)
Rat (6)
Bovine (6)
Chimpanzee (6)
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Peptide-ELISA (1)
rabbit (29)
mouse (24)
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IHCPlus (3)
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monoclonal mc (24)
polyclonal pc (29)
OTI1A2 (2)
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aa116-142 (7)
aa257-306 (4)
aa41-90 (4)
aa84-133 (4)
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Yes (2)
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ZFP36 / Tristetraprolin Rabbit anti-Human Polyclonal (aa41-90) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ZFP36 / Tristetraprolin Rabbit anti-Human Polyclonal (aa84-133) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ZFP36 / Tristetraprolin Antibody - Heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ZFP36 / Tristetraprolin Rabbit anti-Human Polyclonal (aa84-133) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (OTI1H6) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (Carrier-free) (OTI1H6) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ZFP36 / Tristetraprolin Antibody - Immunohistochemical staining of paraffin-embedded colon tissue using anti-ZFP36 mouse monoclonal antibody. (Dilution 1:50).
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (OTI8B5) Antibody
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ZFP36 / Tristetraprolin Antibody - Immunohistochemical staining of paraffin-embedded colon tissue using anti-ZFP36 mouse monoclonal antibody. (Dilution 1:50).
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (Carrier-free) (OTI8B5) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ZFP36 / Tristetraprolin Antibody - IHC of paraffin-embedded Human breast tissue using anti-ZFP36 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (OTI1A2) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ZFP36 / Tristetraprolin Antibody - IHC of paraffin-embedded Human breast tissue using anti-ZFP36 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (Carrier-free) (OTI1A2) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ZFP36 / Tristetraprolin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFP36 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFP36.
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (OTI5E3) Antibody
Human
WB
Unconjugated
100 µl/$434
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ZFP36 / Tristetraprolin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (OTI1C8) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (Carrier-free) (OTI1C8) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (OTI4E1) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (Carrier-free) (OTI4E1) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 antibody IHC of human small intestine, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ZFP36 / Tristetraprolin Rabbit anti-Human Polyclonal (aa257-306) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (OTI3C3) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (Carrier-free) (OTI3C3) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ZFP36 / Tristetraprolin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFP36 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFP36.
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (OTI4B10) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
ZFP36 / Tristetraprolin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFP36 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFP36.
Select
ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (Carrier-free) (OTI4B10) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
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ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (OTI1F2) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (Carrier-free) (OTI1F2) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
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ZFP36 / Tristetraprolin Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (OTI3D10) Antibody
Human
Flo, IF
Unconjugated
100 µl/$450
ZFP36 / Tristetraprolin Antibody - Anti-ZFP36 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ZFP36.
Select
ZFP36 / Tristetraprolin Mouse anti-Human Monoclonal (Carrier-free) (OTI3D10) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).