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| Catalog Number | Size | Price |
|---|---|---|
| LS-C392520-100 | 100 µg | $575 |
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Polyclonal Rabbit anti‑Human VCP Antibody (aa732‑760, IHC, WB) LS‑C392520
Polyclonal Rabbit anti‑Human VCP Antibody (aa732‑760, IHC, WB) LS‑C392520
Antibody:
VCP Rabbit anti-Human Polyclonal (aa732-760) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
VCP Rabbit anti-Human Polyclonal (aa732-760) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus
Format:
Unconjugated, Unmodified
Specifications
Description
VCP antibody LS-C392520 is an unconjugated rabbit polyclonal antibody to VCP (aa732-760) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB.
Target
Human VCP
Synonyms
VCP | 15S Mg(2+)-ATPase p97 subunit | ALS14 | TER ATPase | TERA | Valosin containing protein | Yeast Cdc48p homolog | Valosin-containing protein | IBMPFD | p97
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide (RRDHFEEAMRFARRSVSDNDIRKYEMFAQ, aa732-760 of UniProt P55072) was used as the immunogen for the VCP antibody (100% homologous in human, mouse and rat). Percent identity by BLAST analysis: Human, Mouse, Rat, Ferret, Sheep, Cat, Bovine, Bat, Hamster, Elephant, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Lizard, Xenopus, Dog (100%); Trout, Pufferfish (97%).
Epitope
aa732-760
Specificity
Human VCP
Applications
- IHC
- IHC - Paraffin (0.5 - 1 µg/ml)
- IHC - Frozen (0.5 - 1 µg/ml)
- Western blot (0.5 - 1 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Valosin-containing protein, also called Cdc48, is an enzyme that in humans is encoded by the VCP gene. It is a member of the AAA+ (ATPase associated with various activities) protein family. The gene maps to chromosome 9p13.3. It is necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. It is involved in the formation of the transitional endoplasmic reticulum. This gene plays a role in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. VCP is also involved in DNA damage response: recruited to double-strand breaks (DSBs) sites in a RNF8- and RNF168-dependent manner and promotes the recruitment of TP53BP1 at DNA damage sites.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About VCP
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus, Zebrafish, Drosophila, Insect
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human, Chimpanzee, Gibbon, Monkey, Mouse, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 9/20/2024
Date Requested: 9/20/2024
