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| Catalog Number | Size | Price |
|---|---|---|
| LS-C501870-50 | 50 µg | $294 |
| LS-C501870-100 | 100 µg | $360 |
Polyclonal Rabbit anti‑Human TOLLIP Antibody (IHC) LS‑C501870
Polyclonal Rabbit anti‑Human TOLLIP Antibody (IHC) LS‑C501870
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
TOLLIP antibody LS-C501870 is an unconjugated rabbit polyclonal antibody to human TOLLIP. Validated for ELISA and IHC.
Target
Human TOLLIP
Synonyms
TOLLIP | Adapter protein | IL-1RAcPIP | Toll interacting protein | Toll-interacting protein
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Toll-interacting protein (86-163AA)
Specificity
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Applications
- IHC
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TOLLIP
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, ELISA
Species:
Human
Applications:
Immunofluorescence, Western blot
Species:
Mouse, Human, Gibbon, Monkey, Rat, Bovine, Guinea pig, Hamster, Horse, Rabbit, Zebrafish
Applications:
Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/1/2024
Date Requested: 5/1/2024
