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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNFSF11 / RANKL / TRANCE Antibody (aa161‑177) LS‑C829
TRANCE antibody LS-C829 is an unconjugated rabbit polyclonal antibody to mouse TRANCE (TNFSF11 / RANKL). Validated for WB.
Catalog
Size
Price
LS-C829-100
100 µg (0.5 mg/ml)
$335

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Product Description

TRANCE antibody LS-C829 is an unconjugated rabbit polyclonal antibody to mouse TRANCE (TNFSF11 / RANKL). Validated for WB.

Specifications

Target
Mouse TNFSF11 / RANKL / TRANCE
Synonyms
TNFSF11, CD254, CD254 antigen, HRANKL2, OPTB2, TRANCE, ODF, OPGL, SOdf, Osteoprotegerin ligand, RANKL
Host
Rabbit
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Predicted
Monkey, Rat (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (5 µg/ml)
Immunogen
A synthetic peptide corresponding to amino acids 161-177 of mouse RANKL (AQPFAHLTINAASIPSG).Percent identity by BLAST analysis: Mouse (100%); Marmoset, Rat (94%); Human, Gorilla, Gibbon, Hamster (88%); Monkey, Elephant, Panda, Bovine, Dog, Horse, Rabbit, Pig (82%).
Epitope
aa161-177
Specificity
The amino acid sequence used is 88% homologous in human and 94% homologous in rat.
Presentation
PBS, 0.05% Sodium Azide, 0.2% Gelatin
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About TNFSF11 / RANKL / TRANCE
TNFSF11 / RANKL / TRANCE is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. O14788 AF053712 AAC39731.1


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Images

Western blot

Western blot of Trance in a partial His-tagged recombinant protein using antibody at0.5 ug/ml.
Western blot of Trance in a partial His-tagged recombinant protein using antibody at0.5 ug/ml.

Western blot

Western blot of Trance in a partial His-tagged recombinant protein using antibody at0.5 ug/ml.
Western blot of Trance in a partial His-tagged recombinant protein using antibody at0.5 ug/ml.

Western blot

Western blot of Trance in a partial His-tagged recombinant protein using antibody at0.5 ug/ml.
Western blot of Trance in a partial His-tagged recombinant protein using antibody at0.5 ug/ml.

Western blot

Western blot of Trance in a partial His-tagged recombinant protein using antibody at0.5 ug/ml.
Western blot of Trance in a partial His-tagged recombinant protein using antibody at0.5 ug/ml.

Requested From: United States
Date Requested: 10/19/2018

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