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Catalog Number Size Price
LS-C391360-20 20 µg (0.2 mg/ml) $371 
LS-C391360-100 100 µg (0.2 mg/ml) $574 
TNFRSF18 / GITR Antibody - SDS-PAGE Analysis of Purified, BSA-Free GITR Antibody (clone DTA-1). Confirmation of Integrity and Purity of the Antibody.

Monoclonal Rat anti‑Mouse TNFRSF18 / GITR Antibody (clone DTA‑1, IF) LS‑C391360

Monoclonal Rat anti‑Mouse TNFRSF18 / GITR Antibody (clone DTA‑1, IF) LS‑C391360

Antibody:
TNFRSF18 / GITR Rat anti-Mouse Monoclonal (DTA-1) Antibody
Application:
IF, Flo
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$371
LS-C391360-20
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
TNFRSF18 / GITR Rat anti-Mouse Monoclonal (DTA-1) Antibody
Application:
IF, Flo
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
GITR antibody LS-C391360 is an unconjugated rat monoclonal antibody to mouse GITR (TNFRSF18). Validated for Flow and IF.
Target
Mouse TNFRSF18 / GITR
Synonyms
TNFRSF18 | AITR | CD357 | CD357 antigen | GITR | GITR-D
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2b,l Monoclonal
Clone
DTA-1
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified. Also available Azide-free, BSA-free.
Immunogen
Mouse CD25+ CD4+ T cells were used as the immunogen for the GITR antibody.
Specificity
Mouse TNFRSF18 / GITR
Applications
  • Immunofluorescence (0.5 - 1 µg/ml)
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
Usage
GITR (glucocorticoid-induced TNFR-related gene) is a member of the TNF-receptor superfamily, also known as TNFRSF18. It is expressed at low levels on resting T lymphocytes and at high levels on CD25+ CD4+ Tregs. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production as well as MAPKs and NF-kB activation, and abrogate the inhibitory function of CD25+ CD4+ Tregs. In vivo activation of GITR causes development of autoimmune diseases and restores the suppressed immune response. Optimal dilution of the GITR antibody should be determined by the researcher.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TNFRSF18 / GITR
Q9Y5U5 NM_004195 NP_004186.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 3/1/2024