Recombinant Monoclonal Rabbit anti‑Human TIMP2 Antibody (clone TIMP2/2488R, Azide‑free,Carrier‑free, N‑Terminus, aa56‑66, IHC) LS‑C751391
Recombinant Monoclonal Rabbit anti‑Human TIMP2 Antibody (clone TIMP2/2488R, Azide‑free,Carrier‑free, N‑Terminus, aa56‑66, IHC) LS‑C751391
Antibody:
TIMP2 Rabbit anti-Human Recombinant Monoclonal (N-Terminus, aa56-66) (Azide-free, Carrier-free) (TIMP2/2488R) Antibody
Format:
Unconjugated, Azide-free, Carrier-free
Overview
Antibody:
TIMP2 Rabbit anti-Human Recombinant Monoclonal (N-Terminus, aa56-66) (Azide-free, Carrier-free) (TIMP2/2488R) Antibody
Format:
Unconjugated, Azide-free, Carrier-free
Specifications
Description
TIMP2 antibody LS-C751391 is an unconjugated rabbit recombinant monoclonal antibody to human TIMP2 (N-Terminus, aa56-66). Validated for IHC.
Target
Human TIMP2
Synonyms
TIMP2 | Metalloproteinase inhibitor 2 | TIMP-2 | CSC-21K
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Recombinant Monoclonal
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Azide-free, Carrier-free.
Also available
Unmodified.
Immunogen
A synthetic peptide from the N-Terminus of human TIMP2 protein (aa 56-66). Antigen Molecular Weight: 21 kDa
Epitope
N-Terminus, aa56-66
Specificity
It recognizes a protein of 21 kDa , identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Applications
- IHC - Paraffin (1 - 2 µg/ml)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Usage
Immunohistology (Formalin-fixed - 1-2 ug/ml for 30 minutes at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Storage
Store at -20°C to -80°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Zebrafish
Applications:
IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human, Monkey, Mouse, Rat, Dog
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human, Mouse, Pig, Rabbit, Chicken, Zebrafish
Applications:
IHC - Paraffin, Western blot, ELISA
Species:
Human, Monkey, Mouse, Rat, Dog
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human, Mouse, Rat, Bovine, Guinea pig, Pig, Rabbit
Applications:
IHC, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/7/2024