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Catalog Number Size Price
LS-C392396-20 20 µg (0.2 mg/ml) $371 
LS-C392396-100 100 µg (0.2 mg/ml) $574 
SUMO2 Antibody - Formalin-fixed, paraffin-embedded human testicular carcinoma stained with SUMO-2/3 antibody (SPM572).  This image was taken for the unmodified form of this product. Other forms have not been tested.

Monoclonal Mouse anti‑Human SUMO2 Antibody (clone SPM572, IHC, IF, WB) LS‑C392396

Monoclonal Mouse anti‑Human SUMO2 Antibody (clone SPM572, IHC, IF, WB) LS‑C392396

Antibody:
SUMO2 Mouse anti-Human Monoclonal (SPM572) Antibody
Application:
IHC, IHC-P, IF, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$371
LS-C392396-20
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
SUMO2 Mouse anti-Human Monoclonal (SPM572) Antibody
Application:
IHC, IHC-P, IF, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
SUMO2 antibody LS-C392396 is an unconjugated mouse monoclonal antibody to human SUMO2. Validated for Flow, IF, IHC and WB.
Target
Human SUMO2
Synonyms
SUMO2 | HSMT3 | SMT3 homolog 2 | SMT3A | Sentrin 2 | Smt3B | SMT3H2 | SUMO-2 | SUMO-3 | Sentrin-2 | Ubiquitin-like protein SMT3A | Ubiquitin-like protein SMT3B
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Clone
SPM572
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified. Also available Azide-free, BSA-free.
Immunogen
Recombinant human protein.
Specificity
Human SUMO2
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • Immunofluorescence (0.5 - 1 µg/ml)
  • Western blot (0.5 - 1 µg/ml)
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
This mAb reacts with both SUMO-2 and SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimer s disease. The optimal dilution of the SUMO-2/3 antibody for each application should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SUMO2
P61956 NM_006937 NP_008868.3

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 2/21/2024