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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SLC18A1 / VMAT1 Antibody (C‑Terminus) LS‑C18502
VMAT1 antibody LS-C18502 is an unconjugated rabbit polyclonal antibody to rat VMAT1 (SLC18A1). Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C18502-100
100 µl
$725

Popular SLC18A1 / VMAT1 Products

Anti-SLC18A1 / VMAT1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1189 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Rat, Mouse
Applications: IHC, Western blot, ELISA
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA021426LA01HU at dilution of 1:100
Species: Human, Mouse
Applications: IHC, Western blot, ELISA
Anti-SLC18A1 / VMAT1 antibody IHC of human brain-cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6611 concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Chimpanzee, Gibbon, Mouse, Rat, Bovine
Applications: IHC, IHC - Paraffin, Western blot

Product Description

VMAT1 antibody LS-C18502 is an unconjugated rabbit polyclonal antibody to rat VMAT1 (SLC18A1). Validated for ELISA and WB.
About SLC18A1 / VMAT1
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001). P54219 NM_003053 NP_003044.1

SLC18A1 Antibody, CGAT Antibody, Vesicular amine transporter 1 Antibody, VMAT1 Antibody


Specifications

Target
Rat SLC18A1 / VMAT1
Host
Rabbit
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:50000)
Immunogen
SLC18A1 / VMAT1 antibody was raised against a 12 AA peptide sequence near the C-terminus of rat VMAT1 (1). This peptide is predicted to be cytoplasmic. The peptide was synthesized with amino terminal Cysteine, coupled to KLH.
Epitope
C-Terminus
Specificity
Recognizes rat VMAT1. Does not recognize VMAT2 in transfected cells. The C-terminal rat VMAT1 sequence does not show any appreciable homology with hVMAT1. Antibodies to rVMAT1 are not expected to cross-react with hVMAT1.
Usage
Suitable for use in ELISA, Western Blot. Western Blot: 1:1000-1:5000 for neat serum and 1-10 ug/ml for affinity pure using ECL. A band of 95-110kD has been detected in brush border membrane. ELISA:1:10000-1:50000 for neat serum and 0.5-1 ug/ml for affinity purified. Control peptide can be used to coat ELISA plates at 1 ug/ml.
Presentation
Lyophilized from PBS, 0.05% Sodium Azide
Reconstitution
100 µl Reconstitute in 100 ul of Sterile PBS.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/25/2018

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