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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PSME1 Antibody (PE) LS‑C656595
PSME1 antibody LS-C656595 is a PE-conjugated rabbit polyclonal antibody to PSME1 from human, mouse, rat and other species. Validated for WB.
Antibody
Catalog
Size
Price
LS-C656595-100
100 µl
$755

Popular PSME1 Products

Immunohistochemical analysis of PA28 alpha staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, Flow Cytometry, ELISA
Anti-PSME1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8233 dilution 5-7.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Bat, Pig
Applications: IHC, IHC - Paraffin, Western blot
PSME1 Antibody IHC of formalin-fixed and paraffin-embedded hepatocarcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA

Product Description

PSME1 antibody LS-C656595 is a PE-conjugated rabbit polyclonal antibody to PSME1 from human, mouse, rat and other species. Validated for WB.
About PSME1
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Q06323 NM_006263 NP_006254.1

PSME1 Antibody, 29-kD MCP activator subunit Antibody, IFI5111 Antibody, IGUP I-5111 Antibody, REG-alpha Antibody, REGalpha Antibody, PA28A Antibody, Interferon-gamma IEF SSP 5111 Antibody, PA28alpha Antibody, Proteasome activator subunit-1 Antibody


Specifications

Target
Human PSME1
Host
Rabbit
Reactivity
Human, Mouse, Rat, Pig, Macaque (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Phycoerythrin. Also available Unconjugated or conjugated with AP, APC, Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
PSME1 antibody was raised against synthetic peptide derived from the C-terminal region of the proteasome activator 28-alpha subunit (PA28a, also known as 11s regulator complex alpha subunit (REG-alpha) (11S REG) and Interferon gamma up-regulated I-5111 protein (IGUP I-5111) protein.
Specificity
Reacts with the C-terminal region of mouse, rat, human, crab-eating macaque (monkey) and pig PA28a. On Western blots, it identifies the target band at ~28kD. Faint bands of unknown origin may be observed in some homogenate or lysate preparations. Reactivity has been confirmed with mouse spleen, liver and lung homogenates, as well as with human BC-1 B-lymphocyte lymphoma lysates. Based on amino acid sequence homology, cross-reactivity with rat is expected.
Presentation
PBS, pH 7.2, No preservatives added
Storage
Store at 4°C.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/19/2018

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