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PSME1

proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Alternative splicing results in multiple transcript variants.

Gene Name: proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
Synonyms: PSME1, 29-kD MCP activator subunit, IFI5111, IGUP I-5111, REG-alpha, REGalpha, PA28A, PA28alpha, Proteasome activator subunit-1
Target Sequences: NM_006263 NP_006254.1 Q06323

☰ Filters
Antibodies (35)
Proteins (6)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (35)
Recombinant (4)
Sandwich (1)
PSME1 (42)
Human (36)
Mouse (18)
Rat (15)
Bat (4)
Bovine (1)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Hamster (1)
Macaque (5)
Monkey (5)
Pig (10)
Rabbit (1)
IHC (20)
IHC-P (9)
WB (33)
Flo (7)
ELISA (14)
ICC (2)
IF (3)
IP (3)
Peptide-ELISA (2)
rabbit (32)
mouse (2)
goat (1)
Product Group
IHCPlus (1)
IgG (20)
IgG2a (1)
IgG2a,k (1)
monoclonal mc (2)
polyclonal pc (33)
1G11 (1)
AT12H3 (1)
96-Well Strip Plate (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (22)
aa220-249 (7)
aa72-121 (4)
C-Terminus (1)
Lys13 (1)
aa1-50 (1)
aa232-245 (1)
No (42)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (3)
PSME1 Antibody - Immunohistochemical analysis of PA28 alpha staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PSME1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
PSME1 Antibody
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PSME1 Mouse anti-Mouse Monoclonal (1G11) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µg/$436
PSME1 Antibody - Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
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PSME1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$294; 100 µl/$360
PSME1 Antibody - Anti-PSME1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSME1 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PSME1 Antibody - Anti-PSME1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSME1 Rabbit anti-Human Polyclonal (aa72-121) (HRP) Antibody
Mouse, Pig, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
PSME1 Antibody - Anti-PSME1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSME1 Rabbit anti-Human Polyclonal (aa72-121) (Biotin) Antibody
Mouse, Pig, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
PSME1 Antibody - Anti-PSME1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSME1 Rabbit anti-Human Polyclonal (aa72-121) (FITC) Antibody
Mouse, Pig, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
PSME1 Antibody - PSME1 Antibody IHC of formalin-fixed and paraffin-embedded hepatocarcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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PSME1 Rabbit anti-Human Polyclonal (aa220-249) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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PSME1 Rabbit anti-Human Polyclonal (aa220-249) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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PSME1 Rabbit anti-Human Polyclonal (aa220-249) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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PSME1 Rabbit anti-Human Polyclonal (aa220-249) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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PSME1 Rabbit anti-Human Polyclonal (aa220-249) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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PSME1 Rabbit anti-Human Polyclonal (aa220-249) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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PSME1 Rabbit anti-Human Polyclonal (aa220-249) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
PSME1 Antibody - Immunohistochemistry of paraffin-embedded mouse heart.
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PSME1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PSME1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.19 - 12.5 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
PSME1 Antibody - Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100
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PSME1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
PSME1 Antibody - The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PSME1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : HeLa cell lysate Lane 2. : LNCap cell lysate Lane 3. : A549 cell lysate Lane 4. : 293T cell lysate Lane 5. : Jurkat cell lysate Lane 6. : Raji cell lysate Lane 7. : A431 cell lysate
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PSME1 Mouse anti-Human Monoclonal (AT12H3) Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
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PSME1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
PSME1 Antibody - 1:100 staining rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PSME1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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PSME1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
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PSME1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PSME1 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using PSME1 Polyclonal Antibody at dilution of 1:50(×200)
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PSME1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
PSME1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$412
Select
PSME1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$412
Viewing 1-25 of 42 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).