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Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.Isoform F plays a role as a growth factor acting on the primitive cells of both hematopoietic and endothelial cell lineages.
Gene Name: | proteoglycan 4 |
Synonyms: | PRG4, BG174L6.2, CACP, HAPO, JCAP, Proteoglycan 4, Superficial zone proteoglycan, SZP, Lubricin, MSF |
Target Sequences: | NM_005807 NP_005798.3 Q92954 |
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