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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PKG / PRKG1 Antibody (aa1‑300) LS‑C377477
PRKG1 antibody LS-C377477 is an unconjugated rabbit polyclonal antibody to PRKG1 (PKG) from human and mouse. Validated for ELISA and WB.
Catalog
Size
Price
LS-C377477-50
50 µl
$285
LS-C377477-100
100 µl
$385

Popular PKG / PRKG1 Products

Anti-PRKG1 / CGKI antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2219 concentration 10 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit, Chicken
Applications: IHC, IHC - Paraffin, Western blot
Anti-PRKG1 / CGKI antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4398 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Western blot: Lane 1: MW marker, Lane 2: HeLa cell lysate, Lane 3: Rat brain tissue extract, Lane 4: MDBK cell lysate.
Species: Human, Mouse, Rat, Bovine
Applications: IHC, ICC, Western blot, Immunoprecipitation
Antibody
Species: Human, Mouse, Rat, Bovine
Applications: Western blot
Antibody
Species: Human
Applications: IHC, ICC, Western blot, Immunoprecipitation

Product Description

LifeSpan Antibody

Specifications

Target
Human PKG / PRKG1
Synonyms
PRKG1, CGKI, CGMP kinase I, CGMP protein kinase type I, CGK-I, CGK1, PKGI, PKG I, PRKGR1B, PRKG1B, PRKGR1A, PGK, PKG, CGK, CGK 1, CGKI-alpha, CGKI-BETA
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:2000)
  • ELISA
Immunogen
PKG / PRKG1 antibody was raised against recombinant human cGMP-dependent protein kinase 1 protein (aa1-300).
Epitope
aa1-300
Specificity
Human PKG / PRKG1
Presentation
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only.
About PKG / PRKG1
Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serines and threonines on many cellular proteins. Numerous protein targets for PRKG1 phosphorylation are implicated in modulating cellular calcium, but the contribution of each of these targets may vary substantially among cell types. Q13976 NM_006258 NP_006249.1


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Images

Western blot

Western blot. All lanes: cGMP-dependent protein kinase 1 antibody at 3 ug/ml+mouse lung tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 76 kDa. Observed band size: 76 kDa.
Western blot. All lanes: cGMP-dependent protein kinase 1 antibody at 3 ug/ml+mouse lung tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 76 kDa. Observed band size: 76 kDa.

Western blot

Western blot. All lanes: cGMP-dependent protein kinase 1 antibody at 3 ug/ml+mouse lung tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 76 kDa. Observed band size: 76 kDa.
Western blot. All lanes: cGMP-dependent protein kinase 1 antibody at 3 ug/ml+mouse lung tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 76 kDa. Observed band size: 76 kDa.

Western blot

Western blot. All lanes: cGMP-dependent protein kinase 1 antibody at 3 ug/ml+mouse lung tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 76 kDa. Observed band size: 76 kDa.
Western blot. All lanes: cGMP-dependent protein kinase 1 antibody at 3 ug/ml+mouse lung tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 76 kDa. Observed band size: 76 kDa.

Western blot

Western blot. All lanes: cGMP-dependent protein kinase 1 antibody at 3 ug/ml+mouse lung tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 76 kDa. Observed band size: 76 kDa.
Western blot. All lanes: cGMP-dependent protein kinase 1 antibody at 3 ug/ml+mouse lung tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 76 kDa. Observed band size: 76 kDa.

Requested From: United States
Date Requested: 10/16/2018

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