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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PDX1 Antibody (aa1‑284, Biotin) LS‑C424592
PDX1 antibody LS-C424592 is a biotin-conjugated rabbit polyclonal antibody to mouse PDX1. Validated for ICC and WB.
Antibody
Catalog
Size
Price
LS-C424592-100
100 µl (0.5 mg/ml)
$375

Popular PDX1 Products

Anti-PDX1 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3086 concentration 5 ug/ml.
Species: Human, Monkey, Rabbit
Applications: IHC, IHC - Paraffin, ELISA
Dot blot of anti-Phospho-IPF-pT11 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Species: Human
Applications: Dot Blot
Immunohistochemistry: PDX1 Antibody - IHC analysis of PDX1 in mouse pancreas.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
IHC of paraffin-embedded Human pancreas tissue using anti-PDX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min)(1:150).
Species: Human
Applications: IHC, IHC - Paraffin
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Monkey, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit, Xenopus
Applications: IHC, IHC - Paraffin, Western blot

Product Description

PDX1 antibody LS-C424592 is a biotin-conjugated rabbit polyclonal antibody to mouse PDX1. Validated for ICC and WB.
About PDX1
Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. P52945 NM_000209 NP_000200.1

PDX1 Antibody, Glucose-sensitive factor Antibody, Insulin upstream factor 1 Antibody, IPF1 Antibody, Insulin promoter factor 1 Antibody, IPF-1 Antibody, IUF-1 Antibody, STF-1 Antibody, GSF Antibody, IDX-1 Antibody, Islet/duodenum homeobox-1 Antibody, IUF1 Antibody, MODY4 Antibody, PDX-1 Antibody


Specifications

Target
Mouse PDX1
Host
Rabbit
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, Biotin, FITC, Cy3, HRP, APC, PE, APC, Cy7.
Purification
Affinity purified
Modifications
Unmodified
Applications
  • ICC (1:50 - 1:500)
  • Western blot (1:50 - 1:400)
  • (applications tested for the base form of this product only)
Immunogen
PDX1 antibody was raised against recombinant IPF (Met1-Arg284)
Epitope
aa1-284
Specificity
Mouse PDX1
Usage
Applications and images are for the unconjugated form of this antibody. The conjugated antibody has not been tested. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.4, 0.02% Sodium Azide, 50% Glycerol
Storage
Store at 4°C for frequent use; -20°C to -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/24/2018

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