Human MPO / Myeloperoxidase
MPO | Myeloperoxidase precursor | Myeloperoxidase
(tested or 100% immunogen sequence identity)
Recognizes human myeloperoxidase (MPO). MPO is an important component of azurophilic granules in neutrophils, being involved in microbicidal processes. The protein is a multimer of 2 heavy chains (55kD) and two light chains (15kD), the heavy chains being linked by a disulphide bond. Recognizes native MPO in Western blots, and the heavy chain following boiling of the sample. Also recognizes recombinant MPO in Western blots and weakly in ELISA. May be of value in the study of myeloid cells and myeloid leukemias by flow cytometry following cell permeablization.