Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IHC - Paraffin
IHC - Frozen (1:2 - 1:5)
Specificity and Use
Human IgE antibody was raised against human immunoglobulins.
Recognizes human IgE e-chains; De-1 epitope on Fc fragment. No cross-reaction with other immunoglobulins.
Suitable for use in Immunofluorescence, ELISA, RIA and Immunohistochemistry. Immunohistochemistry (frozen and paraffin): 1:2-1:5. Note: Proteolytic treatment with trypsin required.
PBS, 1% BSA, 0.1% sodium azide, before the addition of glycerol to 40%.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.
About Human IgE
Immunoglobulin E (IgE) is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. Monomers of IgE consist of two heavy chains (epsilon chain) and two light chains, with the epsilon chain containing 4 Ig-like constant domains. IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE is utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum.