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Human IgE

Immunoglobulin E (IgE) is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. Monomers of IgE consist of two heavy chains (epsilon chain) and two light chains, with the epsilon chain containing 4 Ig-like constant domains. IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE is utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum. IgE also has an essential role in type I hypersensitivity, which manifests various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic drugs, bee stings, and antigen preparations used in desensitization immunotherapy. Although IgE is typically the least abundant isotype—blood serum IgE levels in a normal ("non-atopic") individual are only 0.05% of the Ig concentration, compared to 75% for the IgGs at 10 mg/ml, which are the isotypes responsible for most of the classical adaptive immune response—it is capable of triggering the most powerful inflammatory reactions.

Human IgE Target Details

Target Name: Human IgE

Filtered By: None
Target
human-ige (137)
Reactivity
Human (136)
Monkey (7)
Rhesus monkey (1)
Application
IHC (36)
IHC-Fr (4)
IHC-P (5)
WB (41)
Flo (32)
DB (2)
ELISA (114)
ICC (7)
ID (18)
IF (18)
IP (22)
Peptide-ELISA (2)
RIA (5)
Turbidimetry (1)
Host
rabbit (15)
mouse (80)
goat (41)
chicken (1)
Isotype
IgG (39)
IgG1 (21)
IgG1,k (2)
IgG2a (25)
IgG2b (23)
IgG2b,k (1)
Clonality
monoclonal mc (80)
polyclonal pc (57)
Clone
1497CT272.23.66 (1)
1497CT744.79.17 (1)
1A2 (1)
4C3 (1)
4F4 (2)
4G7 (3)
4H10 (4)
5D4 (2)
BE5 (5)
E411 (1)
F4-#16 (2)
Fc-2001 (2)
MH25/1 (1)
MHE-18 (1)
NI 307 (6)
XTE4 (2)
Format
AP Conjugated (12)
APC Conjugated (7)
Azide-free (1)
Biotin Conjugated (12)
DY488 Conjugated (2)
DY550 Conjugated (1)
DY633 Conjugated (1)
DY650 Conjugated (2)
DY800 Conjugated (1)
FITC Conjugated (15)
HRP Conjugated (17)
PE Conjugated (9)
Rhodamine Conjugated (1)
TRITC Conjugated (4)
Unconjugated (53)
Epitope
aa246-275 (8)
Publications
No (137)
Showing 1-25 out of 137 results
Mouse Anti-Human IgE Secondary Antibody (clone BE5) LS-C45962

Mouse Monoclonal [clone BE5] (IgG1) to Human IgE
Human
ELISA Flo
Unconjugated
Mouse Anti-Human IgE Secondary Antibody (clone BE5, FITC) LS-C46388

Mouse Monoclonal [clone BE5] (IgG) to Human IgE
Human
Flo
FITC Conjugated
Mouse Anti-Human IgE Secondary Antibody (clone BE5, PE) LS-C46492

Mouse Monoclonal [clone BE5] (IgG) to Human IgE
Human
Flo
PE Conjugated
Goat Anti-Human IgE Secondary Antibody LS-C59147

Goat Polyclonal to Human IgE
Human, Rhesus monkey
ELISA WB
Unconjugated
Mouse Anti-Human IgE Secondary Antibody (clone MHE-18) LS-C40848

Mouse Monoclonal [clone MHE-18] (IgG1) to Human IgE
Human
ELISA Flo
Unconjugated
Mouse Anti-Human IgE Secondary Antibody (clone BE5) LS-C52210

Mouse Monoclonal [clone BE5] (IgG) to Human IgE
Human
ELISA
Unconjugated
Goat Anti-Human IgE Secondary Antibody (FITC) LS-C123814

Goat Polyclonal (IgG) to Human IgE
Human
Flo ICC IF IHC
FITC Conjugated
Goat Anti-Human IgE Secondary Antibody (HRP) LS-C315495

Goat Polyclonal to Human IgE
Human
ELISA Flo ID IHC IP WB
HRP Conjugated
Goat Anti-Human IgE Secondary Antibody (DY488) LS-C315487

Goat Polyclonal to Human IgE
Human
ELISA Flo ID IF IHC IP WB
DY488 Conjugated
Goat Anti-Human IgE Secondary Antibody LS-C316443

Goat Polyclonal to Human IgE
Human
ELISA Flo ID IHC IP WB
Unconjugated
Goat Anti-Human IgE Secondary Antibody (HRP) LS-C315482

Goat Polyclonal to Human IgE
Human
ELISA Flo ID IHC IP WB
HRP Conjugated
Goat Anti-Human IgE Secondary Antibody (AP) LS-C315479

Goat Polyclonal to Human IgE
Human
ELISA Flo ID IHC IP WB
AP Conjugated
Mouse Anti-Human IgE Secondary Antibody (clone 1A2, HRP) LS-C57677

Mouse Monoclonal [clone 1A2] (IgG1) to Human IgE
Human
ELISA
HRP Conjugated
Chicken Anti-Human IgE Secondary Antibody LS-C96119
Human plasma protein as test antigen.
Purified human IgE protein as test antigen. Affi-pure IgY as primary antibody and Goat anti-IgY-HRP as 2nd antibody. Fixed amount of Ab (1 ug/ml) and serial dilutions of antigen.

Chicken Polyclonal to Human IgE
Human
ELISA WB
Unconjugated
Goat Anti-Human IgE Secondary Antibody LS-C129939

Goat Polyclonal (IgG) to Human IgE
Human
ELISA
Unconjugated
Mouse Anti-Human IgE Secondary Antibody (HRP) LS-C68493

Mouse Monoclonal (IgG1) to Human IgE
Human
ELISA
HRP Conjugated
Rabbit Anti-Human IgE Secondary Antibody (Azide-free, HRP) LS-C259934

Rabbit Polyclonal (IgG) to Human IgE
Human
WB
HRP Conjugated, Azide-free
Mouse Anti-Human IgE Secondary Antibody LS-C68463

Mouse Monoclonal (IgG2b) to Human IgE
Human
ELISA IF IHC IHC-Fr IHC-P RIA
Unconjugated
Goat Anti-Human IgE Secondary Antibody (HRP) LS-C68495

Goat Polyclonal (IgG) to Human IgE
Human
ELISA
HRP Conjugated
Mouse Anti-Human IgE Secondary Antibody (clone 4C3) LS-C57676

Mouse Monoclonal [clone 4C3] (IgG1) to Human IgE
Human
ELISA WB
Unconjugated
Rabbit Anti-Human IgE Secondary Antibody LS-C95869

Rabbit Polyclonal to Human IgE
Human
IHC IHC-P
Unconjugated
Mouse Anti-Human IgE Secondary Antibody (clone 4G7) LS-C45963

Mouse Monoclonal [clone 4G7] (IgG) to Human IgE
Human
ELISA
Unconjugated
Mouse Anti-Human IgE Secondary Antibody (clone 5D4) LS-C52215

Mouse Monoclonal [clone 5D4] (IgG2a) to Human IgE
Human
ELISA
Unconjugated
Mouse Anti-Human IgE Secondary Antibody (HRP) LS-C68491

Mouse Monoclonal (IgG2b) to Human IgE
Human
ELISA
HRP Conjugated
Goat Anti-Human IgE Secondary Antibody (FITC) LS-C129933

Goat Polyclonal (IgG) to Human IgE
Human, Monkey
Flo
FITC Conjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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