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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MNAT1 Antibody (Glu123) LS‑C176775
MNAT1 antibody LS-C176775 is an unconjugated rabbit polyclonal antibody to MNAT1 from human, mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C176775-100
100 µl
$345

Popular MNAT1 Products

Immunofluorescence analysis of MCF7 cells.
Species: Human, Mouse
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation
Antibody
Species: Human
Applications: Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Immunohistochemistry image of paraffin-embedded human testis tissue at a dilution of 1:100
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Immunohistochemical analysis of MNAT1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Rat, Bovine, Pig
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Immunohistochemistry - Paraffin Image
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot

Product Description

LifeSpan Antibody

Specifications

Target
Human MNAT1
Synonyms
MNAT1, Cyclin G1 interacting protein, Cyclin-G1-interacting protein, MAT1, p35, p36, RING finger protein 66, RING finger protein MAT1, Menage a trois, RNF66, TFB3, CAP35, CDK7/cyclin-H assembly factor
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MNAT1 antibody was raised against synthetic peptide around Glu123 of human PEA15
Epitope
Glu123
Specificity
Human PEA15
Presentation
PBS, pH 7.2, 0.05% Sodium Azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About MNAT1
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. P51948 NM_002431 NP_002422.1


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Images

Western blot

Western blot of Mat1 (E123) pAb in extracts from HeLa cells.
Western blot of Mat1 (E123) pAb in extracts from HeLa cells.

Western blot

Western blot of Mat1 (E123) pAb in extracts from HeLa cells.
Western blot of Mat1 (E123) pAb in extracts from HeLa cells.

Western blot

Western blot of Mat1 (E123) pAb in extracts from HeLa cells.
Western blot of Mat1 (E123) pAb in extracts from HeLa cells.

Western blot

Western blot of Mat1 (E123) pAb in extracts from HeLa cells.
Western blot of Mat1 (E123) pAb in extracts from HeLa cells.

Requested From: United States
Date Requested: 10/15/2018

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