Human KRT19 / CK19 / Cytokeratin 19

Rabbit

Human (tested or 100% immunogen sequence identity)

Orangutan, Monkey, Mouse (at least 90% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

A synthetic peptide corresponding to a sequence at the C-Terminus of human Cytokeratin 19 (379-392 aa YRSLLEGQEDHYNN). Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%); Orangutan, Marmoset, Mouse (93%); Baboon, Rat, Rabbit (86%).

aa379-392

Human KRT19 / CK19 / Cytokeratin 19

• IHC
• IHC - Paraffin (0.5 - 1 µg/ml)
• IHC - Frozen (0.5 - 1 µg/ml)
• ICC (0.5 - 1 µg/ml)
• Western blot (0.5 - 1 µg/ml)

Keratin, type I cytoskeletal 19 is a protein that in humans is encoded by the KRT19 gene.The protein encoded by this gene is a member of the keratin family. It is specifically expressed in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.

Reconstitute in sterile distilled water.

Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P08727 NCBI: NM_002276 NP_002267.2