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Catalog Number Size Price
LS-B2003-50 50 µg (0.5 mg/ml) $460 
KRT19 / CK19 / Cytokeratin 19 Antibody - Anti-Cytokeratin 19 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
KRT19 / CK19 / Cytokeratin 19 Antibody - MCF-7 cells were stained with anti-Cytokeratin 19 (clone A53-B/A2), followed by Alexa Fluor 546 secondary antibody and DAPI (nuclei). Images were acquired on a Nikon FC300 inverted microscope at 20X magnification. Data provided by Dr. John Nolan, La Jolla Bioengineering Institute.
KRT19 / CK19 / Cytokeratin 19 Antibody - MCF-7 cell extract was resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-cytokeratin 19 antibody (clone A53-B/A2). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system.
KRT19 / CK19 / Cytokeratin 19 Antibody - Anti-Cytokeratin 19 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
KRT19 / CK19 / Cytokeratin 19 Antibody - MCF-7 cells were stained with anti-Cytokeratin 19 (clone A53-B/A2), followed by Alexa Fluor 546 secondary antibody and DAPI (nuclei). Images were acquired on a Nikon FC300 inverted microscope at 20X magnification. Data provided by Dr. John Nolan, La Jolla Bioengineering Institute.
KRT19 / CK19 / Cytokeratin 19 Antibody - MCF-7 cell extract was resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-cytokeratin 19 antibody (clone A53-B/A2). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system.
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PathPlus™ Monoclonal Mouse anti‑Human KRT19 / CK19 / Cytokeratin 19 Antibody (clone A53‑B/A2, IHC, WB) LS‑B2003

PathPlus™ Monoclonal Mouse anti‑Human KRT19 / CK19 / Cytokeratin 19 Antibody (clone A53‑B/A2, IHC, WB) LS‑B2003

Note: This antibody replaces LS-C41106
Antibody:
KRT19 / CK19 / Cytokeratin 19 Mouse anti-Human Monoclonal (A53-B/A2) Antibody
Application:
IHC, IHC-P, ICC, WB, IP, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B2003-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
KRT19 / CK19 / Cytokeratin 19 Mouse anti-Human Monoclonal (A53-B/A2) Antibody
Application:
IHC, IHC-P, ICC, WB, IP, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
KRT19 is a type 1 keratin, an intermediate filament that provides structural support and has cell cycle regulatory functions in epithelial cells. KRT19 is a common epithelial marker with cytoplasmic positivity in immunohistochemistry. It is used to identify neoplastic epithelial cells in a number of cancers, including breast carcinomas, thyroid papillary carcinomas, cholangiocarcinomas, endometrial cancers, urothelial and collecting duct renal cancers, Paget’s disease, pancreatic cancers, and epithelial odontogenic tumors. Additionally, it is a putative cancer stem cell marker in hepatocellular carcinoma. In normal tissue, KRT19 is positive in epithelia of the breast, GI tract, kidney, bile ducts, pancreatic ducts, salivary and sweat glands, prostate epithelium, placental trophoblasts, uterus, and tonsillar squamous epithelium. References: Clin Cancer Res. 2015 Jul 1;21(13):3081-91, PMID: 25820415; Int J Mol Sci. 2018 May; 19(5): 1423, PMID: 29747452; Cancers (Basel). 2019 Jan; 11(1): 99, PMID: 30650643
Target
Human KRT19 / CK19 / Cytokeratin 19
Synonyms
KRT19 | CK19 | Cytokeratin 19 | Cytokeratin-19 | Keratin 19 | Keratin-19 | CK-19 | K19 | K1CS | Keratin, type I, 40-kd
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Clone
A53-B/A2
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Cells
Specificity
Human mammary carcinoma cell line MCF-7
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • ICC
  • Western blot
  • Immunoprecipitation
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistochemistry: LS-B2003 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2003 was determined to be 10 ug/ml.
Presentation
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide at 0.5 mg/ml.
Storage
Store at 4°C. Store undiluted.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KRT19 / CK19 / Cytokeratin 19
P08727 NM_002276 NP_002267.2

Validation

KRT19 / CK19 / Cytokeratin 19 Antibody - Anti-Cytokeratin 19 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Cytokeratin 19 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Cytokeratin 19 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

LSBio Ratings

PathPlus™ KRT19 / CK19 / Cytokeratin 19 Antibody (clone A53-B/A2) for IHC, ICC, WB/Western, IP, ELISA LS-B2003 has an LSBio Rating of
Laboratory Validation Score (5)

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Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 8/15/2022