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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KDR / VEGFR2 / FLK1 Antibody (aa1300‑1367) LS‑C2934
FLK1 antibody LS-C2934 is an unconjugated rabbit polyclonal antibody to FLK1 (KDR / VEGFR2) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C2934-100
100 µl (2.55 mg/ml)
$335

Popular KDR / VEGFR2 / FLK1 Products

Anti-KDR / VEGFR2 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin
Anti-VEGFR2 antibody IHC of human placenta, endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B669 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Anti-KDR / VEGFR2 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Dog
Applications: IHC, IHC - Paraffin
Antibody
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot
Formalin-fixed, paraffin-embedded human angiosarcoma stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Mouse, Human, Rat
Applications: IHC, IHC - Paraffin, Western blot

Product Description

FLK1 antibody LS-C2934 is an unconjugated rabbit polyclonal antibody to FLK1 (KDR / VEGFR2) from human, mouse and rat. Validated for WB.

Specifications

Target
Mouse KDR / VEGFR2 / FLK1
Synonyms
KDR, CD309, Fetal liver kinase 1, Fetal liver kinase-1, FLK-1, FLK1, Kinase insert domain receptor, Quek1, VEGFR, VEGFR2, Soluble VEGFR2, VEGF receptor 2, VEGFR-2, CD309 antigen, VEGF-R2
Host
Rabbit
Reactivity
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, DY650, DY488, DY550.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:250 - 1:1000)
  • (applications tested for the base form of this product only)
Immunogen
A synthetic peptide made to a C-terminal region of the murine VEGFR2 protein sequence (between residues 1300-1367) Percent identity by BLAST analysis: Mouse, Rat, Human (100%).
Epitope
aa1300-1367
Specificity
VEGR-2.
Presentation
Tris-Glycine, 150 mM NaCl, 0.05% Sodium Azide
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
About KDR / VEGFR2 / FLK1
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. P35968 NM_002253 NP_002244.1


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Images

Western blot

Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using antibody at 1 ug/ml. ECL detection 1 minute.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using antibody at 1 ug/ml. ECL detection 1 minute. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2934 (0.5 ug/ml). ECL detection 10 seconds.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2934 (0.5 ug/ml). ECL detection 10 seconds. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using antibody at 1 ug/ml. ECL detection 1 minute.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using antibody at 1 ug/ml. ECL detection 1 minute. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2934 (0.5 ug/ml). ECL detection 10 seconds.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2934 (0.5 ug/ml). ECL detection 10 seconds. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using antibody at 1 ug/ml. ECL detection 1 minute.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using antibody at 1 ug/ml. ECL detection 1 minute. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2934 (0.5 ug/ml). ECL detection 10 seconds.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2934 (0.5 ug/ml). ECL detection 10 seconds. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using antibody at 1 ug/ml. ECL detection 1 minute.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using antibody at 1 ug/ml. ECL detection 1 minute. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2934 (0.5 ug/ml). ECL detection 10 seconds.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2934 (0.5 ug/ml). ECL detection 10 seconds. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 10/19/2018

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