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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ITPR2 / IP3 Receptor Type 2 Antibody (C‑Terminus) LS‑C24911
IP3 Receptor Type 2 antibody LS-C24911 is an unconjugated rabbit polyclonal antibody to IP3 Receptor Type 2 (ITPR2) from human, mouse, rat and other species. Validated for ICC, IF, IHC, IP and WB. Cited in 1 publication.
Antibody
Catalog
Size
Price
LS-C24911-50
50 µl
$530

Popular ITPR2 / IP3 Receptor Type 2 Products

Anti-ITPR2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human, Mouse, Rat
Applications: Western blot, ELISA
Anti-ITPR2 / IP3 Receptor antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, ICC, Western blot
ITPR2 / IP3 Receptor antibody Western Blot of Fetal Small Intestine. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Horse, Rabbit
Applications: Western blot

Product Description

IP3 Receptor Type 2 antibody LS-C24911 is an unconjugated rabbit polyclonal antibody to IP3 Receptor Type 2 (ITPR2) from human, mouse, rat and other species. Validated for ICC, IF, IHC, IP and WB. Cited in 1 publication.

Specifications

Target
Rat ITPR2 / IP3 Receptor Type 2
Synonyms
ITPR2, IP3R 2, InsP3R2, IP3R2, InsP3R type II, IP3 receptor, InsP3R type 2, IP3 receptor isoform 2, Type 2 InsP3 receptor
Host
Rabbit
Reactivity
Rat, Human, Monkey, Mouse, Hamster (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • ICC
  • Immunofluorescence (1:10 - 1:20)
  • Western blot (1:50 - 1:100)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor.
Epitope
C-Terminus
Specificity
Directed against a synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor. Species cross-reactivity: Human, mouse, hamster and monkey.
Usage
Suitable for use in Western Blot, Immunofluorescence, Immunoprecipitation, Immunocytochemistry and Immunohistochemistry. Western Blot: 1:50-1:100 (detects a 260kD band). Immunofluorescence: 1:10-1:20. Immunohistochemistry: Paraformaldehyde or methanol fixed sections. Immunocytochemistry: Known to give positive reactivity on AR4-2J, HL-60, COS-I, HEK-293 and RBL-2H3 cell lines.
Presentation
PBS, 0.05% BSA, 0.005% sodium azide, 10% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About ITPR2 / IP3 Receptor Type 2
ITPR2 / IP3 Receptor Type 2 belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. Q14571 NM_002223 NP_002214.2


Publications (1)

1
Shared functional defect in IP₃R-mediated calcium signaling in diverse monogenic autism syndromes. Schmunk G, Boubion BJ, Smith IF, Parker I, Gargus JJ. Translational psychiatry. 2015 5:e643. (ICC; Rat) [Full Text Article] [PubMed:26393489] [PMC:PMC5068815]

Customer Reviews (0)


Requested From: United States
Date Requested: 11/16/2018

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