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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IRF2 Antibody (aa249‑266) LS‑C312960
Note: This antibody replaces LS-C388732
IRF2 antibody LS-C312960 is an unconjugated rabbit polyclonal antibody to IRF2 from human, rat, guinea pig and other species. Validated for WB.
Catalog
Size
Price
LS-C312960-100
100 µg (0.5 mg/ml)
$305

Popular IRF2 Products

Staining (2?g/ml) of Jurkat lysate (RIPA buffer, 30?g total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Product Description

IRF2 antibody LS-C312960 is an unconjugated rabbit polyclonal antibody to IRF2 from human, rat, guinea pig and other species. Validated for WB.
About IRF2
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. P14316 NM_002199 NP_002190.2

IRF2 Antibody, IRF-2 Antibody, Interferon regulatory factor 2 Antibody


Specifications

Target
Human IRF2
Host
Rabbit
Reactivity
Human, Monkey, Rat, Guinea pig, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunogen affinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
IRF2 antibody was raised against a synthetic peptide corresponding to a sequence at the C-terminus of human IRF2(249-266aa RPHWRKRNIEGKQYLSNM), identical to the related rat sequence and different from the related mouse sequence by one amino acid.
Epitope
aa249-266
Specificity
Expressed throughout the epithelium of the colon. Also expressed in lamina propria. .
Presentation
Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 ug antibody.
Reconstitution
200 µl Distilled water
Storage
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Western blot

WB of IRF2 antibody. Lane 1:HELA Cell Lysate. Lane 2:MCF-7 Cell Lysate.
WB of IRF2 antibody. Lane 1:HELA Cell Lysate. Lane 2:MCF-7 Cell Lysate.

Western blot

WB of IRF2 antibody. Lane 1:HELA Cell Lysate. Lane 2:MCF-7 Cell Lysate.
WB of IRF2 antibody. Lane 1:HELA Cell Lysate. Lane 2:MCF-7 Cell Lysate.

Western blot

WB of IRF2 antibody. Lane 1:HELA Cell Lysate. Lane 2:MCF-7 Cell Lysate.
WB of IRF2 antibody. Lane 1:HELA Cell Lysate. Lane 2:MCF-7 Cell Lysate.

Western blot

WB of IRF2 antibody. Lane 1:HELA Cell Lysate. Lane 2:MCF-7 Cell Lysate.
WB of IRF2 antibody. Lane 1:HELA Cell Lysate. Lane 2:MCF-7 Cell Lysate.

Requested From: United States
Date Requested: 7/22/2018

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