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Catalog Number Size Price
LS-B2640-50 50 µl (1.3 mg/ml) $485 
ITPR1 / IP3 Receptor Type 1 Antibody - Anti-ITPR1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC‑plus™ Polyclonal Rabbit anti‑Human ITPR1 / IP3 Receptor Type 1 Antibody (aa1892‑1911, IHC, WB) LS‑B2640

IHC‑plus™ Polyclonal Rabbit anti‑Human ITPR1 / IP3 Receptor Type 1 Antibody (aa1892‑1911, IHC, WB) LS‑B2640

Note: This antibody replaces LS-C8244
Antibody:
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (aa1892-1911) Antibody
Application:
IHC, IHC-P, IHC-Fr, ICC, WB, IP
Reactivity:
Human, Monkey, Mouse, Rat, Bovine
Format:
Unconjugated, Unmodified
Price
Catalog Number
$485
LS-B2640-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (aa1892-1911) Antibody
Application:
IHC, IHC-P, IHC-Fr, ICC, WB, IP
Reactivity:
Human, Monkey, Mouse, Rat, Bovine
Format:
Unconjugated, Unmodified

Specifications

Description
IP3 Receptor Type 1 antibody LS-B2640 is an unconjugated rabbit polyclonal antibody to IP3 Receptor Type 1 (ITPR1) (aa1892-1911) from human. It is reactive with human, mouse, rat and other species. Validated for ICC, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Target
Human ITPR1 / IP3 Receptor Type 1
Synonyms
ITPR1 | InsP3R-I | IP3R1 | InsP3R | InsP3R type I | INSP3R1 | IP3R | Opisthotonus | Pcp1 | IP3 receptor | IP3 receptor isoform 1 | SCA15 | Spinocerebellar ataxia 15 | Spinocerebellar ataxia 16 | I145TR | IP3R 1 | KIAA1754 | SCA16 | Type 1 InsP3 receptor
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to aa 1892-1911 (N1892KKKDDEVDRDAPSRKKAKE1911) of the cytoplasmic C-Terminus domain of human IP3R-I (inositol 1,4,5-triphosphate receptor (type-I)). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine (100%); Hamster, Elephant, Panda, Horse (95%); Opossum (85%).
Epitope
aa1892-1911
Specificity
Recognizes human IP3R-I. Detects a band of ~240kD by Western Blot. Species cross-reactivity: mouse, rat and canine.
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • IHC - Frozen (1:125)
  • ICC
  • Western blot (1:500)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistochemistry: LS-B2640 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2640 was determined to be 5 ug/ml.
Presentation
PBS, 1 mg/ml BSA, 0.05% Sodium Azide
Storage
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ITPR1 / IP3 Receptor Type 1
Q14643 NM_001099952 NP_002213.5

Validation

ITPR1 / IP3 Receptor Type 1 Antibody - Anti-ITPR1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ITPR1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ITPR1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

LSBio Ratings

IHC-plus™ ITPR1 / IP3 Receptor Type 1 Antibody (aa1892-1911) for IHC, ICC, WB/Western, IP LS-B2640 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (4)

Publications (1)

PC-PLC is involved in osteoclastogenesis induced by TNF- alpha through upregulating IP3R1 expression. Xia L, Zhang D, Wang C, Wei F, Hu Y. FEBS letters. 2012 Sep;586:3341-8.

Customer Reviews (0)


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Requested From: United States
Date Requested: 5/23/2024