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Catalog Number Size Price
LS-B2859-50 50 µg (1.45 mg/ml) $460 
IL1R1 Antibody - Anti-IL1R1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC‑plus™ Monoclonal Mouse anti‑Human IL1R1 Antibody (clone IL1‑31‑22.2.1, Extracellular Domain, IHC) LS‑B2859

IHC‑plus™ Monoclonal Mouse anti‑Human IL1R1 Antibody (clone IL1‑31‑22.2.1, Extracellular Domain, IHC) LS‑B2859

Note: This antibody replaces LS-C83460
Antibody:
IL1R1 Mouse anti-Human Monoclonal (Extracellular Domain) (IL1-31-22.2.1) Antibody
Application:
IHC, IHC-P, ELISA, RIA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B2859-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
IL1R1 Mouse anti-Human Monoclonal (Extracellular Domain) (IL1-31-22.2.1) Antibody
Application:
IHC, IHC-P, ELISA, RIA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
IL1R1 antibody LS-B2859 is an unconjugated mouse monoclonal antibody to human IL1R1 (Extracellular Domain). Validated for ELISA, IHC and RIA. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Target
Human IL1R1
Synonyms
IL1R1 | Antigen CD121a | D2S1473 | IL-1R-1 | IL-1R-alpha | IL-1RT-1 | IL-1RT1 | IL1R | IL1RA | IL1RT1 | Interleukin receptor 1 | Interleukin-1 receptor alpha | Interleukin-1 receptor type 1 | CD121A | CD121a antigen | Interleukin 1 receptor, type I | Interleukin-1 receptor type I | Interleukin-1 type i receptor | p80
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Clone
IL1-31-22.2.1
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
The extracellular domain of the type I human IL-1 receptor.
Epitope
Extracellular Domain
Specificity
These antibodies react with cell surface and soluble human IL-1 receptor; Specific epitopes are unknown, but they do partially inhibit (30-50%) binding of one another to IL-1 receptor. They do not block binding of IL-1 to receptor, and they do not cross-react with receptors for human IL-2 or IL-4.
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • ELISA
  • Radioimmunoassay
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • Western blot
Usage
Immunohistochemistry: LS-B2859 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2859 was determined to be 10 ug/ml. ELISA: Can be used as capture reagents or second antibody at a concentration of 5 ug/ml. RIA: Concentrations of 20-30 ng/ml of these antibodies will bind radiolabeled IL-1 receptor in a radioimmunoassay format. Immunocytochemistry: IL-1 receptor can be detected on cultured cells using antibody concentrations of 10-100 ug/ml.
Presentation
PBS, pH 7.4
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About IL1R1
P14778 NM_000877 NP_000868.1

Validation

IL1R1 Antibody - Anti-IL1R1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-IL1R1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-IL1R1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

LSBio Ratings

IHC-plus™ IL1R1 Antibody (Extracellular Domain, clone IL1-31-22.2.1) for IHC, ELISA LS-B2859 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (4)

Publications (1)

The role of interleukin-1ß in human trophoblast motility. Prutsch N, Fock V, Haslinger P, Haider S, Fiala C, Pollheimer J, Knöfler M. Placenta. 2012 33:696-703. (ELISA; Human)

Customer Reviews (0)


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Requested From: United States
Date Requested: 7/22/2024