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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IGF2R / CD222 Antibody (APC) LS‑C515838
CD222 antibody LS-C515838 is an APC-conjugated mouse monoclonal antibody to human CD222 (IGF2R). Validated for Flow and WB.
100 µl

Popular IGF2R / CD222 Products

Anti-IGF2R antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5653 dilution 1:100.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Species: Human, Non-Human Primates
Applications: Western blot, Flow Cytometry
Immunohistochemical analysis of CD222 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Bovine
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, ELISA
Permeabilized Peripheral Human Granulocytes stained with Mouse anti Human CD222: APC. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Rhesus monkey
Applications: Flow Cytometry

Product Description

IGF2R / CD222 Antibody (APC) for WB/Western, Flow LS-C515838


Human IGF2R / CD222
IGF2R, CD222 antigen, CIMPR, CI Man-6-P receptor, CI-MPR, IGF-II receptor, MPR 300, MPR1, MPRI, M6P-R, M6P/IGF2R, CD222, M6P/IGF2 receptor
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Allophycocyanin. Also available Unconjugated or conjugated with AP, Biotin, FITC, HRP, PE.
Protein A purified
  • Western blot
  • Flow Cytometry
  • (applications tested for the base form of this product only)
IGF2R / CD222 antibody was raised against recombinant Vaccinia virus encoding CD222
Recognizes an epitope between domains 2 and 5 of CD222 (IGF II receptor), a 250kD ubiquitously expressed multifunctional type I transmembrane protein. The majority of CD222 is found in the late endosomal/prelysosomal compartment; only about 5-10% is in the plasma membrane. The truncated form of the receptor (220kD) is present in human and bovine serum. Reacts with human and non-human primates.
PBS, pH 7.2, No preservatives added, No stabilizing proteins added
Store at 4°C. Do not freeze.
For research use only.
About IGF2R / CD222
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. P11717 NM_000876 NP_000867.2

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Requested From: United States
Date Requested: 10/21/2018

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