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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IGF2R / CD222 Antibody (aa27‑185, Cy3) LS‑C704967
CD222 antibody LS-C704967 is a Cy3-conjugated rabbit polyclonal antibody to human CD222 (IGF2R). Validated for IHC and WB.
Catalog
Size
Price
LS-C704967-20
20 µl
$245
LS-C704967-100
100 µl
$355
LS-C704967-200
200 µl
$445
LS-C704967-1
1 ml
$1,050
LS-C704967-10
10 ml
$4,200

Popular IGF2R / CD222 Products

Antibody
Species: Human, Primate
Applications: Flow Cytometry
Permeabilized Peripheral Human Granulocytes stained with Mouse anti Human CD222: APC. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Rhesus monkey
Applications: Flow Cytometry
Anti-IGF2R antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5653 dilution 1:100.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Immunohistochemical analysis of CD222 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Bovine
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Antibody
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, ELISA

Product Description

CD222 antibody LS-C704967 is a Cy3-conjugated rabbit polyclonal antibody to human CD222 (IGF2R). Validated for IHC and WB.
About IGF2R / CD222
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. P11717 NM_000876 NP_000867.2

IGF2R Antibody, CD222 antigen Antibody, CIMPR Antibody, CI Man-6-P receptor Antibody, CI-MPR Antibody, IGF-II receptor Antibody, MPR 300 Antibody, MPR1 Antibody, MPRI Antibody, M6P-R Antibody, M6P/IGF2R Antibody, CD222 Antibody, M6P/IGF2 receptor Antibody


Specifications

Target
Human IGF2R / CD222
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Cy3. Also available Unconjugated or conjugated with Biotin, FITC, Biotin, FITC, HRP, APC, PE, APC, Cy7.
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
IGF2R / CD222 antibody was raised against recombinant M6PR (Thr27-His185)
Epitope
aa27-185
Specificity
The antibody is a rabbit polyclonal antibody raised against M6PR. It has been selected for its ability to recognize M6PR in immunohistochemical staining and western blotting.
Presentation
PBS, pH 7.4, 0.02% Sodium Azide, 50% Glycerol
Storage
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Western blot

Western blot of IGF2R / CD222 antibody.
Western blot of IGF2R / CD222 antibody.

Western blot

Western blot of IGF2R / CD222 antibody.
Western blot of IGF2R / CD222 antibody.

Western blot

Western blot of IGF2R / CD222 antibody.
Western blot of IGF2R / CD222 antibody.

Western blot

Western blot of IGF2R / CD222 antibody.
Western blot of IGF2R / CD222 antibody.

Requested From: United States
Date Requested: 8/15/2018

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