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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Histone Antibody (Biotin) LS‑C343289
Histone antibody LS-C343289 is a biotin-conjugated mouse monoclonal antibody to human Histone. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C343289-50
50 µg
$305

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Product Description

Histone antibody LS-C343289 is a biotin-conjugated mouse monoclonal antibody to human Histone. Validated for ELISA and WB.
About Histone
Histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation. Without histones, the unwound DNA in chromosomes would be very long (a length to width ratio of more than 10 million to 1 in human DNA).

Specifications

Target
Human Histone
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Biotin. Also available Unconjugated.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (1 - 2 µg/ml)
  • ELISA (1:5000 - 1:8000)
  • (applications tested for the base form of this product only)
Immunogen
Histone antibody was raised against designed and synthetic peptide containing H3R2a.
Specificity
The antibody is not only able to bind to H3R2a, but also distinguish two forms (Asymmetric and Symmetric) of H3R2. It specifically detected protein derived from cell lysates in both ELISA and WB.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. This antibody is shipped with antibody diluent; we recommend the addition of 100 ul of diluent to the 50 ug of lyophilized antibody.
Presentation
Lyophilized from PBS, No preservatives added
Reconstitution
Dilution buffer provided for reconstitution.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/19/2018

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