(tested or 100% immunogen sequence identity)
Also available conjugated with AP
Protein G purified
- Western blot
- (applications tested for the base form of this product only)
Histone antibody was raised against histones purified from calf thymus. MW: 33kD.
Recognizes bovine Histones, H1 and core proteins H2a, H2b, H3, H4. Specificity determined by immunoblot with purified histone run on a gel, followed by immunoperoxidase staining. Species cross-reactivity: human, mouse and hamster.
PBS, pH 7.2, No preservatives added
For research use only.
Histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation. Without histones, the unwound DNA in chromosomes would be very long (a length to width ratio of more than 10 million to 1 in human DNA).