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Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
Gene Name: | dynein, light chain, LC8-type 2 |
Synonyms: | DYNLL2, 8 kDa dynein light chain b, Dynein light chain LC8-type 2, DLC8b, DNCL1B, DLC2, RSPH22, Radial spoke 22 homolog |
Target Sequences: | NP_542408.1 Q96FJ2 |
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