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Catalog Number Size Price
LS-C501216-50 50 µg $294 
LS-C501216-100 100 µg $360 
Antibody

Polyclonal Rabbit anti‑Human DOCK7 Antibody (Biotin) LS‑C501216

Polyclonal Rabbit anti‑Human DOCK7 Antibody (Biotin) LS‑C501216

Antibody:
DOCK7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:
Price
Catalog Number
$294
LS-C501216-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
DOCK7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:

Specifications

Description
DOCK7 antibody LS-C501216 is a biotin-conjugated rabbit polyclonal antibody to human DOCK7. Validated for ELISA.
Target
Human DOCK7
Synonyms
DOCK7 | Dedicator of cytokinesis 7 | KIAA1771 | ZIR2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, HRP.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
Specificity
Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Applications
  • ELISA
  • Applications tested for the base form of this product only
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About DOCK7
Q96N67 AB051558 BAB21862.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/27/2024