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DOCK7

dedicator of cytokinesis 7

Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3.

Gene Name: dedicator of cytokinesis 7
Synonyms: DOCK7, Dedicator of cytokinesis 7, KIAA1771, ZIR2
Target Sequences: AB051558 BAB21862.1 Q96N67

☰ Filters
Products
Antibodies (10)
Primary (10)
DOCK7 (10)
Human (10)
Mouse (2)
Rat (1)
WB (6)
ELISA (6)
IF (1)
IP (3)
Peptide-ELISA (1)
rabbit (9)
mouse (1)
IgG (9)
polyclonal pc (10)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (7)
aa175-225 (1)
aa2090-2140 (1)
No (10)
DOCK7 Antibody - Immunofluorescent analysis of HepG2 cells using DOCK7 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Select
DOCK7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
DOCK7 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
DOCK7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
DOCK7 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
DOCK7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
Select
DOCK7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
DOCK7 Rabbit anti-Human Polyclonal (aa175-225) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
DOCK7 Antibody - Western blot analysis of DOCK7 using HT29 whole cells lysates
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DOCK7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
DOCK7 Rabbit anti-Human Polyclonal (aa2090-2140) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
Select
DOCK7 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).