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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CYR61 Antibody (aa250‑350, DY550) LS‑C142800
CYR61 antibody LS-C142800 is a DY550-conjugated rabbit polyclonal antibody to CYR61 from human and rat. Validated for ICC, IF and WB.
Catalog
Size
Price
LS-C142800-100
100 µl
$365

Popular CYR61 Products

Detection of cleaved CYR61 in MDA-MB-231 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Rat
Applications: ICC, Immunofluorescence, Western blot
Antibody
Species: Mouse
Applications: IHC, Western blot, ELISA
Anti-CYR61 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Mouse, Human, Rat
Applications: IHC, IHC - Paraffin, Western blot
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot
Human Colon, Submucosal Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

CYR61 antibody LS-C142800 is a DY550-conjugated rabbit polyclonal antibody to CYR61 from human and rat. Validated for ICC, IF and WB.

Specifications

Target
Human CYR61
Synonyms
CYR61, GIG1, IGFBP10, Protein CYR61, CCN family member 1, CCN1, IBP-10, IGF-binding protein 10, IGFBP-10, Protein GIG1
Host
Rabbit
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Non-Reactivity
Mouse, Rat
Clonality
Polyclonal
Conjugations
DyLight 550. Also available Unconjugated or conjugated with Biotin, DY650, DY488.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • ICC
  • Immunofluorescence
  • Western blot (1:200)
  • (applications tested for the base form of this product only)
Immunogen
CYR61 antibody was raised against a synthetic peptide made to the human CYR61 protein sequence (between residues 250-350) Percent identity by BLAST analysis: Rat (100%); Mouse (96%).
Epitope
aa250-350
Specificity
Human CYR61 protein.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium borate
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
About CYR61
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. O00622 NM_001554 NP_001545.2


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Images

Western blot

Detection of cleaved CYR61 in MDA-MB-231 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of cleaved CYR61 in MDA-MB-231 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of cleaved CYR61 in MDA-MB-231 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of cleaved CYR61 in MDA-MB-231 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of cleaved CYR61 in MDA-MB-231 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of cleaved CYR61 in MDA-MB-231 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of cleaved CYR61 in MDA-MB-231 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of cleaved CYR61 in MDA-MB-231 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 11/14/2018

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