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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CYR61 Antibody LS‑C121688
CYR61 antibody LS-C121688 is an unconjugated rabbit polyclonal antibody to CYR61 from human, rat and sheep. Validated for IHC and WB.
Antibody
Catalog
Size
Price
LS-C121688-20
20 µl
$415
LS-C121688-100
100 µl
$890

Popular CYR61 Products

Detection of cleaved CYR61 in MDA-MB-231 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Rat
Applications: ICC, Immunofluorescence, Western blot
Antibody
Species: Mouse
Applications: IHC, Western blot, ELISA
Anti-CYR61 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Mouse, Human, Rat
Applications: IHC, IHC - Paraffin, Western blot
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot
Human Colon, Submucosal Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

CYR61 antibody LS-C121688 is an unconjugated rabbit polyclonal antibody to CYR61 from human, rat and sheep. Validated for IHC and WB.

Specifications

Target
Human CYR61
Synonyms
CYR61, GIG1, IGFBP10, Protein CYR61, CCN family member 1, CCN1, IBP-10, IGF-binding protein 10, IGFBP-10, Protein GIG1
Host
Rabbit
Reactivity
Human, Rat, Sheep (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • IHC - Frozen
  • Western blot (1:500)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CYR61 antibody was raised against full-length human cysteine-rich protein 61 (CYR61, CCN1) fused to the Fc-domain of human IgG (CYR61-Fc).
Specificity
Recognizes human Cysteine-rich Protein 61 (CCN1). Species cross-reactivity: sheep, rat.
Usage
Suitable for use in Western Blot, Immunohistochemistry: 1:500. Frozen and paraffin sections. Western Blot: 1:500.
Presentation
Lyophilized PBS, pH 7.2
Reconstitution
20 µl or 100 µl Distilled water
Storage
Lyophilized powder may be stored at 4°C for short-term only. Reconstituted product is stable for 1 year at -20°C.
Restrictions
For research use only.
About CYR61
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. O00622 NM_001554 NP_001545.2


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Requested From: United States
Date Requested: 11/13/2018

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