Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CYR61, GIG1, IGFBP10, Protein CYR61, CCN family member 1, CCN1, IBP-10, IGF-binding protein 10, IGFBP-10, Protein GIG1
Human, Rat, Sheep
(tested or 100% immunogen sequence identity)
IHC - Paraffin
IHC - Frozen
Western blot (1:500)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
CYR61 antibody was raised against full-length human cysteine-rich protein 61 (CYR61, CCN1) fused to the Fc-domain of human IgG (CYR61-Fc).
Recognizes human Cysteine-rich Protein 61 (CCN1). Species cross-reactivity: sheep, rat.
Suitable for use in Western Blot, Immunohistochemistry: 1:500. Frozen and paraffin sections. Western Blot: 1:500.
Lyophilized PBS, pH 7.2
20 µl or 100 µl Distilled water
Lyophilized powder may be stored at 4°C for short-term only. Reconstituted product is stable for 1 year at -20°C.
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1.