Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit, Human, Rat
(tested or 100% immunogen sequence identity)
Western blot (1:1000)
Rabbit Cytochrome b5.
Recognizes rabbit, cytochrome b5. Non-specific cross-reactivity with 50 and 60kD species. Species cross-reactivity: rat and human.
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000. Yields a positive result with 0.2 ug of purified rabbit cytochrome b5 using alkaline phosphatase conjugated donkey anti-goat antibodies according to the manufacturer's instructions. Optimum dilutions to be determined by researcher.
CYB5A / Cytochrome b5 is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
Clinical usefulness of gefitinib for non-small-cell lung cancer with a double epidermal growth factor receptor mutation. Oikawa T, Ohira T, Otani K, Hagiwara M, Konaka C, Ikeda N. Molecular and clinical oncology. 2015 3:329-333. (WB; Rabbit)[Full Text Article]