Target
Human CR1 / CD35
Synonyms
CR1 | C3b/C4b receptor | C3-binding protein | CD35 | C3BR | Knops blood group antigen | C4BR | CD35 antigen | Complement receptor type 1 | KN
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
R. Phycoerythrin.
Also available
Unconjugated or conjugated with
FITC.
Immunogen
Human acute monocytic leukaemia cells.
Specificity
Is a single chain cell surface glycoprotein which exists in four allotypic forms (A, B, C, D) of 190kD, 220kD, 160kD and 250kD respectively. The molecule is expressed by granulocytes, monocytes, B cells and some T cells. Functionally CD35 acts as a receptor for the C3b component of complement.