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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CORNIFIN / SPRR1B Antibody (C‑Terminus, Biotin) LS‑C471133
SPRR1B antibody LS-C471133 is a biotin-conjugated rabbit polyclonal antibody to SPRR1B (CORNIFIN) from human, chimpanzee, gibbon and other species. Validated for WB.
Catalog
Size
Price
LS-C471133-100
100 µl (1 mg/ml)
Unavailable

Popular CORNIFIN / SPRR1B Products

SPRR1B antibody LS-C146187 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey
Applications: Western blot
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with SPRR1B Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

SPRR1B antibody LS-C471133 is a biotin-conjugated rabbit polyclonal antibody to SPRR1B (CORNIFIN) from human, chimpanzee, gibbon and other species. Validated for WB.
About CORNIFIN / SPRR1B
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage. P22528 NM_003125 NP_003116.2

SPRR1B Antibody, 14.9 kd pancornulin Antibody, 14.9 kDa pancornulin Antibody, CORNIFIN Antibody, GADD33 Antibody, SPR-IB Antibody, Small proline-rich protein IB Antibody, SPRR1 Antibody, Cornifin B Antibody, Cornifin-B Antibody, Small proline-rich protein 1B Antibody


Specifications

Target
Human CORNIFIN / SPRR1B
Host
Rabbit
Reactivity
Human, Chimpanzee, Gibbon, Monkey (tested or 100% immunogen sequence identity)
Predicted
Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide from C-Terminus of human SPRR1B (P22528, NP_003116). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%); Panda, Pig (92%); Mouse, Rat, Bovine (84%).
Epitope
C-Terminus
Specificity
Human SPRR1B
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS.
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

SPRR1B antibody LS-C146187 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SPRR1B antibody LS-C146187 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

SPRR1B antibody LS-C146187 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SPRR1B antibody LS-C146187 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

SPRR1B antibody LS-C146187 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SPRR1B antibody LS-C146187 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

SPRR1B antibody LS-C146187 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SPRR1B antibody LS-C146187 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/22/2018

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