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Catalog Number Size Price
LS-C41851-1 1 ml $410 
Complement C5 Antibody - Human Liver, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE)

Polyclonal Sheep anti‑Human Complement C5 Antibody (IHC) LS‑C41851

Polyclonal Sheep anti‑Human Complement C5 Antibody (IHC) LS‑C41851

Note: This antibody replaces LS-C79719, LS-C22318
Antibody:
Complement C5 Sheep anti-Human Polyclonal Antibody
Application:
IHC-P, ID
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$410
LS-C41851-1
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Complement C5 Sheep anti-Human Polyclonal Antibody
Application:
IHC-P, ID
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Complement C5 antibody LS-C41851 is an unconjugated sheep polyclonal antibody to human Complement C5. Validated for ID and IHC.
Target
Human Complement C5
Synonyms
C5 | Anaphylatoxin C5a analog | CPAMD4 | Complement C5 | Complement component 5
Host
Sheep
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Ion exchange chromatography
Modifications
Unmodified
Immunogen
Human C5, purified from plasma.
Specificity
Recognizes complement component 5 (C5), a member of the complement system. The complement system consists of a tightly regulated network of proteins. Its activation leads to a sequential cascade of enzymatic reactions, resulting in opsonisation of the pathogens and their removal by phagocytes, as well as cell lysis. Three pathways have been described, the antibody-dependent pathway (classical pathway), the alternative pathway and the lectin activation pathway. The complement system plays a critical role in both innate and adaptive immune responses. It is also involved in tissue regeneration, tumor growth and some human pathologies. Complement component 5 is the initiator of the effector terminal phase of the complement system. C5 convertase cleaves C5 into C5a, a potent anaphylatoxin, and C5b, ultimately resulting in the formation of the multimeric membrane attack complex (MAC) together with the other components of the terminal pathway (C5b-C9). Gives a single arc when tested by immunoelectrophoresis (IEP) against human plasma. The identity has been confirmed by double diffusion against fresh human plasma and a known anti human C5.
Applications
  • IHC - Paraffin (1:100)
  • Immunodiffusion
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
GBS, 1 mM EDTA, 0.1% EACA, 0.09% Sodium Azide, 0.01% Benzamidine
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About Complement C5
P01031 NM_001735 NP_001726.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/19/2021