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CLCN3 antibody LS-C31442 is an unconjugated rabbit polyclonal antibody to CLCN3 (ClC-3) from human, mouse, rat and other species. Validated for IHC and WB.
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Species:
Human, Mouse, Rat
Applications:
IHC, ICC, Western blot
Species:
Rat, Human, Mouse
Applications:
IHC, ICC, Western blot
Species:
Rat, Human, Mouse
Applications:
IHC, ICC, Western blot
Species:
Rat, Human, Mouse
Applications:
IHC, ICC, Western blot
Product Description
CLCN3 antibody LS-C31442 is an unconjugated rabbit polyclonal antibody to CLCN3 (ClC-3) from human, mouse, rat and other species. Validated for IHC and WB.
About ClC-3 / CLCN3
ClC-3 / CLCN3 is a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function.
P51790
NM_001829
NP_001820.2
CLCN3 Antibody, Chloride channel protein 3 Antibody, ClC-3 Antibody, Chloride channel 3 Antibody, Chloride transporter ClC-3 Antibody, CLC3 Antibody
Specifications
Target
Human ClC-3 / CLCN3
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein A purified
Modifications
Unmodified
Applications
- IHC
- IHC - Paraffin
- Western blot (1.25 µg/ml)
- (applications tested for the base form of this product only)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Immunogen
ClC-3 / CLCN3 antibody was raised against synthetic peptide located between aa620-670 of human CLCN3 (P51790, NP_776297). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Xenopus, Salmon, Zebrafish (100%); Sheep, Sea squirt, Drosophila (90%); Panda, Lizard (81%).
Blocking Peptide
LS-E12632 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C31442. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Immunizing peptide used to generate LS-C31442. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa620-670
Specificity
Human CLCN3
Presentation
Lyophilized from PBS, 0.09% sodium azide, 2% sucrose
Reconstitution
Centrifuge the vial prior to opening. Reconstitute with sterile distilled water to a concentration of 1 mg/ml. Vortex and centrifuge again.
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
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Images
Immunohistochemistry
CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry
CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry
CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry
CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Requested From: United States
Date Requested: 9/20/2018
Date Requested: 9/20/2018
